Resolution-enhanced imaging through scattering media by high-order correlation.

Super-resolution optical imaging is a rapidly emerging technology enabling many applications. Recently, correlation imaging has shown its capability in imaging beyond the diffraction limit, relying on quantum and statistical properties of light. High-order correlation imaging can further enhance resolution, however, at the expense of complicated algorithms. Here, we experimentally demonstrate a resolution-enhanced method of imaging through scattering media by exploiting high-order correlation of fluorescence light. Based on this method, individual fluorophores' temporal fluctuations are recorded and computed for their distinguished high-order correlations that enable super-resolution. Special designed time sequences are chosen to reduce computation time and memory. Such high-order correlation imaging exhibits reliable performance through scattering media with significant resolution enhancement and background noise reduction. This efficient imaging method paves the way for new biomedical applications.