早期胃和胃食管交界处恶性肿瘤的治疗。

Management of Early Stage Gastric and Gastroesophageal Junction Malignancies.

机构信息

Department of Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, 4 Silverstein Pavilion, Philadelphia, PA 19104, USA.

出版信息

Surg Clin North Am. 2019 Jun;99(3):439-456. doi: 10.1016/j.suc.2019.02.008. Epub 2019 Apr 1.

DOI:10.1016/j.suc.2019.02.008

PMID:31047034

Abstract

Esophageal and gastric carcinomas are prevalent malignancies worldwide. In contrast to the poor prognosis associated with advanced stages of disease, early stage disease has a favorable prognosis. Early stage gastric cancer (ESGC) is defined as cancer in which the depth of invasion is limited to the submucosal layer of the stomach on histologic examination, regardless of lymph node status. ESGC that meets standard or expanded criteria can be treated via endoscopic mucosal resection and endoscopic submucosal dissection. Similar indications for endoscopic interventions exist for gastroesophageal junction and esophageal malignancies."

摘要

食管和胃腺癌是全球普遍存在的恶性肿瘤。与疾病晚期相关的预后不良形成对比的是，早期疾病具有良好的预后。早期胃癌（ESGC）定义为组织学检查中浸润深度局限于胃黏膜下层的癌症，无论淋巴结状态如何。符合标准或扩展标准的 ESGC 可以通过内镜黏膜切除术和内镜黏膜下剥离术进行治疗。对于胃食管交界处和食管恶性肿瘤，也存在类似的内镜干预适应证。