Aggarwal Richa, Banerjee Arnab, Soni Kapil Dev, Kumar Atin, Trikha Anjan
Critical and Intensive Care, JPNATC, All India Institute of Medical Sciences, New Delhi, India.
Department of Plastic Surgery, All India Institute of Medical Sciences, New Delhi, India.
Chin J Traumatol. 2019 Jun;22(3):172-176. doi: 10.1016/j.cjtee.2019.01.007. Epub 2019 Mar 14.
Fat embolism syndrome (FES) is systemic manifestation of fat emboli in the circulation seen mostly after long bone fractures. FES is considered a lethal complication of trauma. There are various case reports and series describing FES. Here we describe the clinical characteristics, management in ICU and outcome of these patients in level I trauma center in a span of 6 months.
In this prospective study, analysis of all the patients with FES admitted in our polytrauma intensive care unit (ICU) of level I trauma center over a period of 6 months (from August 2017 to January 2018) was done. Demographic data, clinical features, management in ICU and outcome were analyzed.
We admitted 10 cases of FES. The mean age of patients was 31.2 years. The mean duration from time of injury to onset of symptoms was 56 h. All patients presented with hypoxemia and petechiae but central nervous system symptoms were present in 70% of patients. The mean duration of mechanical ventilation was 11.7 days and the mean length of ICU stay was 14.7 days. There was excellent recovery among patients with no neurological deficit.
FES is considered a lethal complication of trauma but timely management can result in favorable outcome. FES can occur even after fixation of the fracture. Hypoxia is the most common and earliest feature of FES followed by CNS manifestations. Any patient presenting with such symptoms should raise the suspicion of FES and mandate early ICU referral.
脂肪栓塞综合征(FES)是循环系统中脂肪栓子的全身性表现,多见于长骨骨折后。FES被认为是创伤的一种致命并发症。有各种关于FES的病例报告和系列研究。在此,我们描述了在一家一级创伤中心6个月内这些患者的临床特征、在重症监护病房(ICU)的治疗及预后情况。
在这项前瞻性研究中,对我们一级创伤中心的多创伤重症监护病房(ICU)在6个月期间(从2017年8月至2018年1月)收治的所有FES患者进行了分析。分析了人口统计学数据、临床特征、在ICU的治疗及预后情况。
我们收治了10例FES患者。患者的平均年龄为31.2岁。从受伤到症状出现的平均时长为56小时。所有患者均出现低氧血症和瘀点,但70%的患者有中枢神经系统症状。机械通气的平均时长为11.7天,ICU住院的平均时长为14.7天。无神经功能缺损的患者恢复良好。
FES被认为是创伤的一种致命并发症,但及时治疗可带来良好预后。即使在骨折固定后也可能发生FES。低氧是FES最常见和最早出现的特征,其次是中枢神经系统表现。任何出现此类症状的患者都应怀疑FES,并要求尽早转诊至ICU。