Kummer V, Zralý Z, Canderle J, Svecová D
Vet Med (Praha). 1987 Jan;32(1):9-17.
The placentomes were extirpated from 16 cows after parturition induced with 750 micrograms cloprostenol or 20 mg dexamethasone on the 277th day of gravidity, on an average, from 9 cows after spontaneous parturition, and from 7 cows after hysterectomy in the eighth month of gravidity. In the cows with induced calving the foetal placenta was not expelled within 12 hours after calving in 68.7% of the cases whereas in the spontaneous parturitions this proportion was only 22.2% of cases. The placentomes obtained immediately after calf expulsion, and then after four and eight hours, were subjected to histological and histochemical examination. In the terminal crypts of the placentome in cross sections obtained from cows which expelled the placenta in time after natural and induced parturitions, the number of binuclear cells of the fetal syncytium and of cells of the dam epithelium (P less than 0.001) was found to be significantly lower than in the cases of afterbirth retention (1.2 and 3.9; 6.4 and 18.5). The cells of the cow's epithelium of the expelled placentae had a higher activity of acid phosphatase and lipids and the foetal syncytium had a higher activity of non-specific esterase. Increased alkaline phosphatase activity was characteristic of the cow's epithelium in the cases of subsequent retention of afterbirth. These findings should be taken into account in efforts for developing new methods of the induction of parturition if the undesired occurrence of afterbirth retention is to be reduced.
在妊娠第277天，给16头奶牛注射750微克氯前列醇或20毫克地塞米松诱导分娩后取出胎盘；平均从9头自然分娩的奶牛以及7头妊娠8个月后进行子宫切除的奶牛身上取出胎盘。在诱导分娩的奶牛中，68.7%的奶牛在产后12小时内未排出胎儿胎盘，而自然分娩的奶牛中这一比例仅为22.2%。在犊牛出生后立即、然后在4小时和8小时后取出胎盘，进行组织学和组织化学检查。在自然分娩和诱导分娩后及时排出胎盘的奶牛的胎盘横切面上，胎盘小叶终末隐窝内胎儿合胞体双核细胞和母体上皮细胞数量（P＜0.001）显著低于胎盘滞留病例（分别为1.2和3.9；6.4和18.5）。排出胎盘的奶牛上皮细胞酸性磷酸酶和脂质活性较高，胎儿合胞体非特异性酯酶活性较高。胎盘滞留病例中，奶牛上皮细胞碱性磷酸酶活性增加。如果要减少胎盘滞留这一不良情况的发生，在开发新的诱导分娩方法时应考虑这些发现。
