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放射治疗治疗评估:临床专科放射治疗师与放射肿瘤学家在患者评估中一致性的前瞻性评价。

Radiotherapy Treatment Review: A Prospective Evaluation of Concordance between Clinical Specialist Radiation Therapist and Radiation Oncologist in Patient Assessments.

作者信息

Lee Grace, Harnett Nicole, Zychla Laura, Dinniwell Robert E

机构信息

Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada.

Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Cancer Care Ontario, Toronto, Ontario, Canada.

出版信息

J Med Imaging Radiat Sci. 2012 Mar;43(1):6-10. doi: 10.1016/j.jmir.2011.10.001.

Abstract

PURPOSE

This study assessed the concordance of patient assessments performed during weekly radiotherapy treatment reviews between the breast site clinical specialist radiation therapist (CSRT) and radiation oncologist (RO).

METHODS AND MATERIALS

A CSRT and RO independently assessed patients attending a breast radiotherapy review clinic and graded their toxicities according to the Common Terminology Criteria for Adverse Events v.3.0. Both observers were blinded to each other's assessments. The concordance rates and agreement levels, indicated by the Kappa statistics, were calculated with the RO considered as the gold standard.

RESULTS

Twenty-nine consecutive patients were prospectively reviewed over 12 weeks. High concordance occurred between CSRT and RO assessments, with an overall concordance rate of 96% for all evaluated toxicities. The concordance rates for non-zero grade toxicities ranged from 76% to 100%. There was almost perfect agreement between the CSRT and RO in toxicity grading for dermatitis (P < .05), whereas fair agreement was observed for hyperpigmentation (P < .05). Overall, there was increasing agreement between the CSRT and RO assessments over time.

CONCLUSION

Common side effects experienced by patients receiving breast radiotherapy as detected and graded by the CSRT were highly comparable to those of the RO. This study lends support for CSRT involvement in treatment review assessments for this patient population.

摘要

目的

本研究评估了在乳腺癌放疗每周治疗复查期间,乳腺专科临床放射治疗师(CSRT)与放射肿瘤学家(RO)所进行的患者评估的一致性。

方法和材料

一名CSRT和一名RO独立评估参加乳腺癌放疗复查门诊的患者,并根据不良事件通用术语标准第3.0版对其毒性进行分级。两名观察者均对彼此的评估不知情。以RO的评估为金标准,计算一致性率和由Kappa统计量表示的一致水平。

结果

在12周内对29例连续患者进行了前瞻性评估。CSRT和RO的评估之间具有高度一致性,所有评估毒性的总体一致性率为96%。非零级毒性的一致性率在76%至100%之间。CSRT和RO在皮炎毒性分级方面几乎完全一致(P <.05),而在色素沉着方面观察到中等程度的一致(P <.05)。总体而言,随着时间的推移,CSRT和RO的评估之间的一致性不断提高。

结论

CSRT检测和分级的接受乳腺癌放疗患者的常见副作用与RO检测和分级的高度可比。本研究为CSRT参与该患者群体的治疗复查评估提供了支持。

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