Vovan A, Tribouilloy C, Avinée P, Dericbourg C, Lalau J D, Lesbre J P
Arch Mal Coeur Vaiss. 1986 Dec;79(13):1868-76.
The aim of this study was to evaluate the diagnostic value of changes in Q wave amplitude in the V5 chest lead in coronary artery disease, especially for the detection of significant (greater than or equal to 75% narrowing) left interior descending disease. The stress tests of 227 patients were reviewed and confronted with the results of coronary angiography in 93 patients with angiographically normal arteries, and 134 patients with left anterior descending disease of the latter, 37 had single vessel disease, 38 had double vessel disease and 59, triple vessel disease. The average values of the Q wave amplitude in V5 at the peak of effort were 0.97 +/- 1.04 mm in the control group; 0.53 +/- 0.65 mm (p less than 0.01) in the group with single vessel disease; 0.46 +/- 0.66 mm (p less than 0.01) in the group with double vessel disease and 0.64 +/- 0.9 mm (p = 0.04) in the group with triple vessel disease. The mean variations of the amplitude of the Q wave in lead V5 on effort in the same group of patients were: +0.55 +/- 0.73 mm (p less than 0.001); + 0.11 +/- 0.66 mm (NS); + 0.02 +/- 0.5 mm (NS) and + 0.05 +/- 0.53 mm (NS), respectively. The Q wave in lead V5 was generally deeper on effort in the control group and the average variation in its amplitude was statistically significant only in this group. In the coronary patients, the Q wave in lead V5 was generally smaller and its amplitude did not change significantly on effort.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是评估V5胸导联Q波振幅变化在冠状动脉疾病中的诊断价值,尤其是用于检测左前降支病变严重(狭窄大于或等于75%)的情况。回顾了227例患者的负荷试验结果,并与93例冠状动脉造影显示血管正常的患者以及134例左前降支病变患者的冠状动脉造影结果进行对照,后者中37例为单支血管病变,38例为双支血管病变,59例为三支血管病变。负荷高峰时V5导联Q波振幅的平均值在对照组为0.97±1.04mm;单支血管病变组为0.53±0.65mm(p<0.01);双支血管病变组为0.46±0.66mm(p<0.01);三支血管病变组为0.64±0.9mm(p=0.04)。同一组患者负荷时V5导联Q波振幅的平均变化分别为:+0.55±0.73mm(p<0.001);+0.11±0.66mm(无显著性差异);+0.02±0.5mm(无显著性差异);+0.05±0.53mm(无显著性差异)。对照组负荷时V5导联的Q波通常更深,且其振幅的平均变化仅在该组具有统计学意义。在冠心病患者中,V5导联的Q波通常较小,且负荷时其振幅无显著变化。(摘要截断于250字)