Ponsonnaille J, Citron B, Karsenty B, D'Agrosa M C, Peycelon P, Veyre A, Gras H
Arch Mal Coeur Vaiss. 1986 Dec;79(13):1946-50.
The authors report the case of a 35 year old man with no known previous cardiac disease. One month after a tic bite causing diffuse abdominal erythema, he was admitted to hospital with fever, breathlessness and bradycardia. The electrocardiogramme showed first degree atrioventricular block with a sinoatrial block (SA = 200 ms, AH = 240 ms). Echocardiography eliminated the diagnosis of pericardial effusion. Thallium 201 myocardial scintigraphy was pathological and showed irregular global uptake suggesting cardiomyopathy. Gallium 67 scintigraphy showed increased uptake in the left ventricle. The evolution was uncomplicated with normalisation of clinical, ECG and radiological changes. Cardiac catheterisation and angiography eliminated ischaemic and primary cardiomyopathy. Control radionuclide investigations were normal at one month: there was no persistent abnormal Gallium uptake. The diagnosis of Lyme's syndrome was confirmed by positive serology with successive titres of 1/1024 and 1/2048 (significant at titres over 1/256). This unusual case illustrates: the risk of myocardial disease in Lyme's syndrome; the diagnostic value of Gallium 67 scintigraphy in acute myocarditis: Gallium seems to fix specifically on inflamed tissues, so distinguishing myocarditis from primary cardiomyopathies.
作者报告了一例35岁男性病例,该患者既往无已知心脏病史。在被蜱虫叮咬导致腹部弥漫性红斑一个月后,他因发热、呼吸急促和心动过缓入院。心电图显示一度房室传导阻滞伴窦房阻滞(SA = 200毫秒,AH = 240毫秒)。超声心动图排除了心包积液的诊断。铊201心肌闪烁扫描显示异常,呈现不规则的整体摄取,提示心肌病。镓67闪烁扫描显示左心室摄取增加。病情演变顺利,临床、心电图和放射学改变均恢复正常。心导管检查和血管造影排除了缺血性和原发性心肌病。一个月时的对照放射性核素检查结果正常:镓摄取无持续异常。莱姆病综合征的诊断通过血清学阳性得到证实,连续滴度为1/1024和1/2048(滴度超过1/256时有意义)。这个不寻常的病例说明了:莱姆病综合征中心肌病的风险;镓67闪烁扫描在急性心肌炎中的诊断价值:镓似乎特别固定在发炎组织上,从而将心肌炎与原发性心肌病区分开来。