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肺癌的微创外科治疗方法。

Minimally invasive surgical approaches for lung cancer.

机构信息

a Division of Thoracic Surgery, Toronto General Hospital , University Health Network , Toronto , Ontario , Canada.

出版信息

Expert Rev Respir Med. 2019 Jun;13(6):571-578. doi: 10.1080/17476348.2019.1610399. Epub 2019 May 6.

Abstract

: Surgery is the standard of care for early-stage non-small cell lung cancer (NSCLC), but there remains on an ongoing discussion as to what is the best surgical approach. Despite only modest adoption of minimally invasive surgery (MIS), it is now the favored approach over traditional open surgery. MIS techniques like video-assisted (VATS) and robot-assisted thoracoscopic surgery (RATS) have been demonstrated to reduce postoperative complications and shorten the length of hospitalization. Furthermore, despite unresolved questions of the oncological equivalency of MIS approaches, recent literature suggests no differences in upstaging or survival between VATS and open surgery. : We examine the current state and future direction of MIS for lung cancer in this review. : The perioperative benefits of VATS may make it superior to thoracotomy. There is overall insufficient clinical and patient equipoise to support a large randomized trial comparing MIS with open surgery at this time, but this may change in the presence of compelling preliminary data. The growing use of RATS has thus far only shown equivalence to VATS at a higher cost. Further investigation is needed.

摘要

手术是早期非小细胞肺癌(NSCLC)的标准治疗方法,但对于最佳手术方法仍存在持续的讨论。尽管微创外科(MIS)的采用程度有限,但它现在是传统开胸手术的首选方法。MIS 技术,如电视辅助胸腔镜手术(VATS)和机器人辅助胸腔镜手术(RATS),已被证明可以减少术后并发症并缩短住院时间。此外,尽管 MIS 方法的肿瘤学等效性仍存在未解决的问题,但最近的文献表明 VATS 与开胸手术之间在分期或生存方面没有差异。

在这篇综述中,我们检查了 MIS 在肺癌中的现状和未来方向。

VATS 的围手术期益处可能使其优于开胸术。目前,总体上缺乏临床和患者均衡的证据来支持将 MIS 与开胸手术进行大型随机试验,但如果有令人信服的初步数据,这种情况可能会改变。RATS 的使用日益增多,但迄今为止,其成本更高,仅与 VATS 等效。需要进一步研究。

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