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Locally Advanced Non Small Cell Lung Cancer: The Case for Radiation Dose De-escalation in the Management of the Mediastinum.

作者信息

Soyfer Viacheslav, Corn Benjamin W

机构信息

Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel.

Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.

出版信息

Front Oncol. 2019 Apr 16;9:283. doi: 10.3389/fonc.2019.00283. eCollection 2019.

DOI:10.3389/fonc.2019.00283
PMID:31058085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6477092/
Abstract
摘要

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Concurrent Daily Cisplatin and High-Dose Radiation Therapy in Patients With Stage III Non-Small Cell Lung Cancer.同期每日顺铂与高剂量放疗治疗 III 期非小细胞肺癌患者。
Int J Radiat Oncol Biol Phys. 2018 Nov 1;102(3):543-551. doi: 10.1016/j.ijrobp.2018.07.188. Epub 2018 Jul 25.
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Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer.Durvalumab 用于 III 期非小细胞肺癌放化疗后的治疗。
N Engl J Med. 2017 Nov 16;377(20):1919-1929. doi: 10.1056/NEJMoa1709937. Epub 2017 Sep 8.
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Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839.术前放化疗±帕尼单抗序贯巩固化疗用于潜在可切除的局部晚期（Ⅲa期，N2+）非小细胞肺癌的随机II期研究：NRG肿瘤学RTOG 0839
J Thorac Oncol. 2017 Sep;12(9):1413-1420. doi: 10.1016/j.jtho.2017.06.007. Epub 2017 Jun 16.
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Is there a different dose-effect relation between the primary tumor and involved lymph nodes in locally advanced non-small-cell lung cancer? A hypothesis-generating study.局部晚期非小细胞肺癌中原发肿瘤与受累淋巴结之间是否存在不同的剂量效应关系？一项产生假设的研究。
Acta Oncol. 2017 Apr;56(4):541-547. doi: 10.1080/0284186X.2017.1293288. Epub 2017 Feb 26.
6
Cardiac Toxicity After Radiotherapy for Stage III Non-Small-Cell Lung Cancer: Pooled Analysis of Dose-Escalation Trials Delivering 70 to 90 Gy.Ⅲ期非小细胞肺癌放疗后的心脏毒性：70至90 Gy剂量递增试验的汇总分析
J Clin Oncol. 2017 May 1;35(13):1387-1394. doi: 10.1200/JCO.2016.70.0229. Epub 2017 Jan 23.
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Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.调强放射治疗技术对局部晚期非小细胞肺癌的影响：NRG肿瘤学RTOG 0617随机临床试验的二次分析
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