Carlson K J
Eur Urol. 1987;13 Suppl 1:45-7. doi: 10.1159/000472859.
A cost effectiveness analysis comparing single-dose with conventional antibiotic treatment for uncomplicated urinary tract infection is described. The analysis is based on aggregated effectiveness and side effect rates reported in the medical literature. A comparison of single-dose and conventional regimens of trimethoprim-sulfamethoxazole and amoxicillin indicates that single-dose regimens are preferable to conventional regimens of either drug, and that trimethoprim-sulfamethoxazole is preferable to amoxicillin, on the grounds both of days of morbidity averted and of medical care costs. Thus single-dose therapy is cost-effective compared to conventional treatment.
本文描述了一项针对单纯性尿路感染，比较单剂量抗生素治疗与传统抗生素治疗的成本效益分析。该分析基于医学文献中报道的综合有效性和副作用发生率。对甲氧苄啶 - 磺胺甲恶唑和阿莫西林的单剂量与传统治疗方案的比较表明，基于避免发病天数和医疗费用两方面的原因，单剂量方案比这两种药物的传统方案更可取，且甲氧苄啶 - 磺胺甲恶唑比阿莫西林更可取。因此，与传统治疗相比，单剂量治疗具有成本效益。
