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复杂结肠癌的急诊手术与肿瘤切除:我们能期待什么?罗马尼亚的中等病例量经验

Emergency Surgery and Oncologic Resection for Complicated Colon Cancer: What Can We Expect? A Medium Volume Experience in Romania.

作者信息

Enciu Octavian, Calu Valentin, Angelescu Mihai, Nădrăgea Mihai Alexandru, Miron Adrian

出版信息

Chirurgia (Bucur). 2019 Mar-Apr;114(2):200-206. doi: 10.21614/chirurgia.114.2.200.

Abstract

Complicated colon cancer most frequently presents as obstruction and needs emergency surgery. Most of these patients receive their diagnosis when presenting for complicated disease and by that time the disease is usually advanced. While concerned first with the survival of the patient, the curative intent of the resection following the principles of oncologic resection may come in second place. Materials and methods: We retrospectively analyzed 68 consecutive patients with complicated colon cancer that suffered emergency surgery between January 2017 and September 2018. The principles of oncologic resection were analyzed in terms of resection margins and retrieved lymph nodes and/or multivisceral resections in order to achieve clear margins. Intestinal obstruction was observed in 58 patients (85.3%), perforation was found in 8 patients (11.8%) while lower gastrointestinal bleeding complicated 2 cases (2.9%). Twenty-two patients had distant metastases at presentation, and overall 29 patients (42,6%) had stage IV disease. Clear circumferential margins were achieved in 55 cases while longitudinal margins were found to be invaded in 2 cases and the mean number of retrieved lymph nodes was greater than 13.7. The mean hospital stay was 13.9 days and the observed in hospital mortality was 19.1%. The outcomes of surgery for complicated colon cancer in our department fall within the reported literature results. Conclusion: The principles of oncologic resection in terms of surgical margins and retrieved lymph nodescan be respected during emergency surgery and offer the intent of cure for these patients with advanced disease.

摘要

复杂性结肠癌最常见的表现为肠梗阻,需要急诊手术。这些患者大多在出现复杂病情时才得到诊断,此时疾病通常已进展。虽然首先关注患者的生存,但遵循肿瘤切除原则进行切除的治愈意图可能位居其次。材料与方法:我们回顾性分析了2017年1月至2018年9月期间连续68例接受急诊手术的复杂性结肠癌患者。从切缘、获取的淋巴结和/或多脏器切除方面分析肿瘤切除原则,以实现切缘阴性。58例患者(85.3%)出现肠梗阻,8例患者(11.8%)发现穿孔,2例患者(2.9%)并发下消化道出血。22例患者就诊时已有远处转移,总体29例患者(42.6%)为IV期疾病。55例实现了清晰的环周切缘,2例发现纵向切缘受侵,获取的淋巴结平均数量大于13.7个。平均住院时间为13.9天,观察到的住院死亡率为19.1%。我们科室复杂性结肠癌的手术结果在已报道的文献结果范围内。结论:在急诊手术期间,可以遵循肿瘤切除原则中关于手术切缘和获取淋巴结的原则,为这些晚期疾病患者提供治愈意图。

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