Suppr超能文献

对于生物力学稳定的腹疝修补术,增大的疝尺寸需要更高的GRIP值。

Increasing hernia size requires higher GRIP values for a biomechanically stable ventral hernia repair.

作者信息

Kallinowski F, Gutjahr D, Vollmer M, Harder F, Nessel R

机构信息

Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Chirurgische Universitätsklinik Heidelberg, Im Neuenheimer Feld 110, D-69120, Heidelberg, Germany.

Technische Universität Hamburg-Harburg, Institut für Biomechanik, Eissendorferstrasse 38, D-21075, Hamburg, Germany.

出版信息

Ann Med Surg (Lond). 2019 Apr 19;42:1-6. doi: 10.1016/j.amsu.2019.04.002. eCollection 2019 Jun.

Abstract

BACKGROUND

Increasing hernia sizes lead to higher recurrence rates after ventral hernia repair. A better grip might reduce the failure rates.

MATERIAL AND METHODS

A biomechanical model delivering dynamic intermittent strain (DIS) was used to assess grip values at various hernia orifices. The model consists of a water-filled aluminium cylinder covered with tissues derived from pig bellies which are punched with a central defect varying in diameter. DIS was applied mimicking coughs lasting for up to 2 s with peak pressures between 180 and 220 mmHg and a plateau phase of 0.1 s. Ventral hernia repair was simulated with hernia meshes in the sublay position secured by tacks, glue or sutures as needed to achieve certain grip values. Grip was calculated taking into account the mesh: defect area ratio and the fixation strength. Data were assessed using non-parametric statistics.

RESULTS

Using a mesh classified as highly stable upon DIS testing (DIS class A) a reduced overlap without fixation led to early slippage (p < 0.001). With the application of 16 fixation points, transmural sutures were better than tacks with Securestrap being better than Absorbatack (p < 0.001). Plotting the likelihood of a durable repair as a function of the calculated grip higher grip values were needed with increasing hernia diameter to achieve biomechanical stability. This is important for clinical work since the calculated grip values both from a registry and from published data tend to drop as hernia sizes increase indicating biomechanical instability.

CONCLUSION

The experimental work reported here demonstrates for the first time that higher grip values should be reached when repairing larger ventral hernias.

摘要

背景

腹疝修补术后,疝大小增加会导致更高的复发率。更好的固定可能会降低失败率。

材料与方法

使用一个提供动态间歇性应变(DIS)的生物力学模型来评估不同疝孔处的固定值。该模型由一个装满水的铝制圆柱体组成,上面覆盖着取自猪腹部的组织,在其中心打一个直径不同的缺损孔。通过模拟持续长达2秒、峰值压力在180至220毫米汞柱之间且平台期为0.1秒的咳嗽来施加DIS。通过在腹膜前间隙放置疝修补网片,并根据需要使用钉合、胶水或缝合来模拟腹疝修补,以达到特定的固定值。固定值的计算考虑了网片与缺损面积比以及固定强度。使用非参数统计评估数据。

结果

在DIS测试中被归类为高度稳定的网片(DIS A类),在没有固定的情况下重叠减少会导致早期滑动(p<0.001)。应用16个固定点时,全层缝合优于钉合,Securestrap钉优于Absorbatack钉(p<0.001)。将持久修复的可能性绘制为计算出的固定值的函数,随着疝直径的增加,需要更高的固定值才能实现生物力学稳定性。这对临床工作很重要,因为来自登记处和已发表数据的计算出的固定值往往会随着疝大小的增加而下降,表明生物力学不稳定。

结论

此处报道的实验工作首次表明,修复较大的腹疝时应达到更高的固定值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb4a/6488564/3293762b0064/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验