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Selecting the dose metric in reverse dosimetry based QIVIVE : Reply to 'Comment on 'Use of an in vitro-in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine' by Ning et al., Arch Toxicol doi: https://doi.org/10.1007/s00204-019-02397-7', Arch Toxicol doi: https://doi.org/10.1007/s0020 4-019-02421-w.

作者信息

Rietjens Ivonne M C M, Ning Jia, Chen Lu, Wesseling Sebastiaan, Strikwold Marije, Louisse Jochem

机构信息

Division of Toxicology, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.

Van Hall Larenstein University of Applied Sciences, 8901 BV, Leeuwarden, The Netherlands.

出版信息

Arch Toxicol. 2019 May;93(5):1467-1469. doi: 10.1007/s00204-019-02438-1. Epub 2019 May 7.

DOI:10.1007/s00204-019-02438-1
PMID:31062055
Abstract
摘要

相似文献

1
Selecting the dose metric in reverse dosimetry based QIVIVE : Reply to 'Comment on 'Use of an in vitro-in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine' by Ning et al., Arch Toxicol doi: https://doi.org/10.1007/s00204-019-02397-7', Arch Toxicol doi: https://doi.org/10.1007/s0020 4-019-02421-w.基于反向剂量测定法的定量体外-体内外相关性研究中剂量指标的选择：对“Ning等人对‘使用体外-计算机模拟测试策略预测吡咯里西啶生物碱阔叶千里光碱和瑞德利碱肝脏毒性的种间和种族间人类差异’的评论”的回复，《毒理学文献》，doi: https://doi.org/10.1007/s00204-019-02397-7，《毒理学文献》，doi: https://doi.org/10.1007/s00204-019-02421-w 。
Arch Toxicol. 2019 May;93(5):1467-1469. doi: 10.1007/s00204-019-02438-1. Epub 2019 May 7.
2
Letter to the Editor : Comment on 'Use of an in vitro-in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine' by Ning et al., Arch Toxicol doi: https://doi.org/10.1007/s00204-019-02397-7.
Arch Toxicol. 2019 May;93(5):1465-1466. doi: 10.1007/s00204-019-02421-w. Epub 2019 May 10.
3
Use of an in vitro-in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine.应用体外-计算毒理学策略预测吡咯里西啶生物碱 lasiocarpine 和 riddelliine 在肝脏毒性方面的种间和种族间的人体差异。
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Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat.运用基于生理学的动力学模型辅助反向剂量学方法，将离体细胞毒性数据转化为拉西卡品和瑞德利碱在大鼠体内肝脏毒性的预测值。
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Arch Toxicol. 2019 Aug;93(8):2385-2395. doi: 10.1007/s00204-019-02515-5. Epub 2019 Jul 9.
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Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity.吡咯里西啶生物碱衍生的 DNA 加合物作为吡咯里西啶生物碱诱导肿瘤形成的常见生物生物标志物。
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