糖尿病母亲所生适于胎龄儿的不对称性室间隔肥厚。
Asymmetric Septal Hypertrophy in Appropriate for Gestational Age Infants Born to Diabetic Mothers.
机构信息
Department of Neonatology, Hospital General de Leon, Leon: Mexico.
Department of Research, University De La Salle Bajio, Leon: Mexico. Correspondence to: Dr Norma Amador Licona, University De La Salle Bajio. Department of Research, Av Universidad 602, Col Lomas del Campestre, ZC 37150, Leon, Gto, Mexico.
出版信息
Indian Pediatr. 2019 Apr 15;56(4):314-316.
OBJECTIVE
To compare the frequency of asymmetric septal hypertrophy in appropriate for gestational age infants born to diabetic mothers with those born to non-diabetic mothers.
METHODS
We compared 38 full term infants born to diabetic mothers with 85 full term infants of non-diabetic mothers. 2-D echocardiography was obtained in the first 24 hours after birth.
RESULTS
Asymmetric septal hypertrophy was only present in infants born to diabetic mothers (50% vs. 0%; P<0.001). Intraventricular septum thickness and intraventricular septum/posterior wall of the left ventricle ratio was also significantly higher in the first group (P<0.001). We found no correlation between mother´s glycated hemoglobin levels and intraventricular septum thickness in newborns.
CONCLUSION
Asymmetric septal hypertrophy is a common finding in infants born to diabetic mothers, even if they are appropriate for gestational age.
目的
比较糖尿病母亲所生的适于胎龄儿与非糖尿病母亲所生的适于胎龄儿中不对称性室间隔肥厚的发生频率。
方法
我们比较了 38 例糖尿病母亲所生的足月新生儿与 85 例非糖尿病母亲所生的足月新生儿。在出生后 24 小时内进行二维超声心动图检查。
结果
不对称性室间隔肥厚仅见于糖尿病母亲所生的婴儿（50%比 0%；P<0.001）。第一组的室间隔厚度和室间隔/左心室后壁比值也显著更高（P<0.001）。我们未发现母亲糖化血红蛋白水平与新生儿室间隔厚度之间存在相关性。
结论
即使是适于胎龄儿，糖尿病母亲所生的婴儿也常见不对称性室间隔肥厚。
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