Manabe Hiroaki, Sakai Toshinori, Morimoto Masatoshi, Tezuka Fumitake, Yamashita Kazuta, Takata Yoichiro, Sairyo Koichi
Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
J Med Invest. 2019;66(1.2):119-122. doi: 10.2152/jmi.66.119.
INTRODUCTION Titanium (Ti) coated polyether ether ketone (PEEK) interbody cages (IBCs) have been introduced to overcome any disadvantages. The purpose of this study was to investigate the radiological outcomes of lumbar interbody fusion (LIF) surgery using the Ti-coated PEEK IBC with a minimum of 1-year of follow-up. METHODS A total of 26 intervertebral spaces in consecutive 21 patients who underwent posterior/transforaminal LIF using the Ti-coated PEEK IBC were evaluated. Rates of bone union, screw loosening, cage subsidence and bone cyst formation around the endplate were evaluated on computed tomography scans acquired at least 1 year postoperatively. RESULTS AND DISCUSSION At the 1-year follow-up, bone fusion was achieved in 23 (88.4%) of 26 intervertebral spaces. Cagesubsidence was found in 5 intervertebral spaces ; however,bone fusion was achieved in all these spaces. Bone cysts formed in 4 intervertebral spaces and 4 of 94 screws were found to be loosened. Three of the loosened screws were found in vertebral bodies adjacent to intervertebral spaces with nonunion. However, there was no association between these events. Although more scientific evidence is required to determine the advantages of Ti-coated PEEK IBCs, we believe the clinical outcomes achieved were favorable at the 1 year minimum follow-up. J. Med. Invest. 66 : 119-122, February, 2019.
引言 钛（Ti）涂层聚醚醚酮（PEEK）椎间融合器（IBCs）已被引入以克服任何缺点。本研究的目的是调查使用钛涂层PEEK IBC进行腰椎椎间融合（LIF）手术且至少随访1年的放射学结果。方法 对连续21例使用钛涂层PEEK IBC进行后路/经椎间孔LIF手术的患者的26个椎间隙进行评估。在术后至少1年获得的计算机断层扫描上评估骨融合率、螺钉松动、融合器下沉和终板周围骨囊肿形成情况。结果与讨论 在1年随访时，26个椎间隙中的23个（88.4%）实现了骨融合。5个椎间隙发现有融合器下沉；然而，所有这些间隙均实现了骨融合。4个椎间隙形成了骨囊肿，94枚螺钉中有4枚被发现松动。3枚松动螺钉位于与未融合椎间隙相邻的椎体中。然而，这些事件之间没有关联。尽管需要更多科学证据来确定钛涂层PEEK IBCs的优势，但我们认为在至少1年的随访中取得的临床结果是良好的。《医学调查杂志》66:119 - 122，2019年2月。
