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成人经导管封堵房间隔缺损全麻苏醒过程中Amplatzer房间隔封堵器反复移位:一例报告

The repeating dislodgement of an Amplatzer Septal Occluder device during recovery from general anesthesia in an adult undergoing transcatheter closure of atrial septal defect : a case report.

作者信息

Abe Natsuki, Go Masanori, Nakai Kaori, Kato Michihisa, Tanaka Katsuya

机构信息

Department of Anesthesiology, Tokushima Prefectural Central Hospital, Tokushima, Japan.

Department of Anesthesiology, Tokushima RedCross Hospital, Tokushima, Japan.

出版信息

J Med Invest. 2019;66(1.2):194-198. doi: 10.2152/jmi.66.194.

DOI:10.2152/jmi.66.194
PMID:31064940
Abstract

Transcatheter closure with an Amplatzer Septal Occluder (ASO) has become the standard treatment for secundum atrial septal defect (ASD). However, this procedure is associated with complications, such as device dislodgement. A 52-year-old woman was admitted with exertional dyspnea. Transesophageal echocardiography showed an ASD involving a 29 mm defect. Calculated Qp/Qs was 5.6 and all the rims were ?5 mm, with the exception of the posterior rim, which was 3 mm. Transcatheter ASD closure with an ASO was performed under general anesthesia. During emergence from anesthesia, tachycardia developed and the ASO device became dislodged. Hemodynamic changes associated with the end of anesthetic administration were believed to have led to device dislodgement. In a second transcatheter ASD closure, a low dose of propofol and remifentanil was maintained during emergence from anesthesia to reduce hemodynamic changes. However, device dislodgement occurred with nonsustained ventricular tachycardia. Finally, surgical ASD closure was performed. The large defect size, high Qp/Qs, and rim deficiency may have predisposed to device dislodgement after transcatheter ASD closure with ASO. The risk of device dislodgement should be considered in advance of surgery and, in high-risk cases, the patient's cardiovascular status should be closely monitored. J. Med. Invest. 66 : 194-198, February, 2019.

摘要

经导管使用Amplatzer房间隔封堵器(ASO)进行封堵已成为继发孔型房间隔缺损(ASD)的标准治疗方法。然而,该手术存在并发症,如封堵器移位。一名52岁女性因劳力性呼吸困难入院。经食管超声心动图显示ASD,缺损大小为29mm。计算得出的肺循环血流量与体循环血流量之比(Qp/Qs)为5.6,除后缘为3mm外,所有边缘均≥5mm。在全身麻醉下进行经导管ASD封堵术,使用ASO。麻醉苏醒期间,出现心动过速,ASO封堵器移位。据信麻醉给药结束时的血流动力学变化导致了封堵器移位。在第二次经导管ASD封堵术中,麻醉苏醒期间维持低剂量丙泊酚和瑞芬太尼以减少血流动力学变化。然而,出现非持续性室性心动过速时封堵器移位。最后,进行了外科ASD封堵术。较大的缺损尺寸、高Qp/Qs和边缘不足可能是经导管使用ASO封堵ASD后封堵器移位的诱因。手术前应提前考虑封堵器移位的风险,在高危病例中,应密切监测患者的心血管状况。《医学调查杂志》66:194 - 198,2019年2月。

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