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药剂师在 HIV 暴露前预防中的作用不断扩大。

The Pharmacist's Expanding Role in HIV Pre-Exposure Prophylaxis.

机构信息

1 LifeCare Clinic, Indiana University Health Methodist Hospital, Indianapolis, Indiana.

2 Department of Pharmacy Services, Temple University Hospital, Philadelphia, Pennsylvania.

出版信息

AIDS Patient Care STDS. 2019 May;33(5):207-213. doi: 10.1089/apc.2018.0294.

Abstract

The efficacy of pre-exposure prophylaxis (PrEP) to prevent HIV has been firmly established; however, the success of PrEP largely depends on access to care as well as high levels of medication adherence. One of the key areas of focus for the National HIV/AIDS Strategy for 2020 in the United States calls for full access to comprehensive PrEP services where appropriate and desired, with support for medication adherence. Despite advances and advocacy for PrEP since approval for adults in 2012, large rates of prescribing disparity exist among gender and race/ethnicity. In 2016, only 3.7% of all PrEP users were women and only 11.2% were black. As one of the most widely accessible health care resources, pharmacists are well positioned to improve patient understanding, promote medication adherence, provide key risk reduction counseling, and enhance PrEP efficacy. Pharmacists' knowledge and accessibility in nearly every urban and rural community can be leveraged as part of a comprehensive HIV prevention strategy to expand access to care and improve population health. As trusted health care professionals, pharmacists develop a strong rapport with patients and may be the key to address current disparities in PrEP prescribing patterns as well as serve as an essential liaison between patients and other members of the multi-disciplinary care team. The purpose of this review is to summarize available data on pharmacist involvement in various models of care providing PrEP services and to identify opportunities to maximize and expand the role of the pharmacist to improve access to PrEP.

摘要

暴露前预防 (PrEP) 预防 HIV 的功效已得到充分证实;然而,PrEP 的成功在很大程度上取决于获得护理以及药物高度依从性。美国 2020 年国家艾滋病毒/艾滋病战略的重点之一是在适当和需要的情况下全面提供综合的 PrEP 服务,并提供药物依从性支持。尽管自 2012 年批准成人使用 PrEP 以来取得了进展和倡导,但在性别和种族/族裔方面,处方差异仍然很大。2016 年,所有 PrEP 用户中只有 3.7%是女性,只有 11.2%是黑人。作为最广泛的医疗保健资源之一,药剂师非常适合提高患者的理解、促进药物依从性、提供关键的风险降低咨询,并提高 PrEP 的效果。药剂师在几乎每个城市和农村社区的知识和可及性可以作为综合艾滋病毒预防策略的一部分加以利用,以扩大护理的获得并改善人口健康。作为值得信赖的医疗保健专业人员,药剂师与患者建立了密切的关系,他们可能是解决当前 PrEP 处方模式差异的关键,也是患者与多学科护理团队其他成员之间的重要联络人。本综述的目的是总结药剂师参与各种提供 PrEP 服务的护理模式的数据,并确定机会以最大限度地发挥和扩大药剂师的作用,以改善 PrEP 的获得。

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