Katsantonis G P, Archer C R, Rosenblum B N, Yeager V L, Friedman W H
Otolaryngol Head Neck Surg. 1986 Jul;95(1):52-62. doi: 10.1177/019459988609500112.
In this retrospective study, the accuracy of preoperative staging by high-resolution CT and clinical evaluation (indirect-direct laryngoscopy) is compared to the postsurgical pathologic staging of laryngeal cancer. Forty-two patients who were admitted to St. Louis University Hospital between the years of 1978 to 1985 with diagnoses of laryngeal cancer were included. All patients received high-resolution CT scan of the larynx preoperatively and subsequently underwent total or partial laryngectomy. None of these patients received preoperative radiotherapy. The accuracy of the clinical vs. CT staging--as well as the accuracy of the staging by combination of the two modalities--was determined by comparison with the postsurgical pathologic staging. The accuracy was assessed separately for glottic, supraglottic, and transglottic carcinoma. The accuracy of CT staging for glottic carcinoma was 75%. However, clinical evaluation in this group of lesions was very reliable, offering 92.9% accuracy. The accuracy of CT staging increased in the supraglottic and transglottic lesions, to become superior to the clinical staging. With combined information gained by both examinations, the preoperative staging accuracy was 91.4% for supraglottic carcinoma and 87.5% for transglottic carcinoma. It is, therefore, recommended that high-resolution CT should be included in the preoperative staging of laryngeal cancer.
在这项回顾性研究中，将高分辨率CT和临床评估（间接喉镜检查和直接喉镜检查）进行术前分期的准确性与喉癌术后病理分期进行了比较。纳入了1978年至1985年间入住圣路易斯大学医院且诊断为喉癌的42例患者。所有患者术前均接受了喉部高分辨率CT扫描，随后接受了全喉或部分喉切除术。这些患者均未接受术前放疗。通过与术后病理分期比较，确定临床分期与CT分期的准确性，以及两种检查方式联合分期的准确性。分别评估声门癌、声门上癌和跨声门癌的分期准确性。声门癌CT分期的准确性为75%。然而，该组病变的临床评估非常可靠，准确率为92.9%。声门上癌和跨声门癌病变中CT分期的准确性有所提高，超过了临床分期。结合两种检查获得的信息，声门上癌术前分期的准确率为91.4%，跨声门癌为87.5%。因此，建议将高分辨率CT纳入喉癌的术前分期。
