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二氧化碳激光治疗喉狭窄

CO2 laser management of laryngeal stenosis.

作者信息

Schmidt F W, Piazza L S, Chipman T J, Campbell B H, Toohill R J

出版信息

Otolaryngol Head Neck Surg. 1986 Nov;95(4):485-90. doi: 10.1177/019459988609500412.

Abstract

The introduction of the carbon dioxide laser as an endoscopic surgical instrument has stimulated interest in its application for removal of stenotic lesions of the larynx. Clinical reports have indicated mixed results in the efficacy of this treatment modality. Nineteen large dogs received acute subglottic injuries from a high-speed electric drill and electrocautery. All animals developed obstructing lesions from 7 to 21 days after injury. With at least weekly removal of granulation tissue and dilations, all animals developed mature subglottic and/or posterior commissure scars. Two animals required tracheostomy. The 15 animals in the experimental group underwent 16 laser procedures. Three animals had vaporization of one third of the scar, three of one half of the scar, and three had total circumferential vaporization. Five animals underwent microtrapdoor flap procedures. Of these, four had a single flap and one had three separate flaps created. In the remaining animal in the experimental group a glottic web developed, which was totally ablated. In one animal treated with a microtrapdoor flap procedure a posterior sinus tract also developed and was treated with laser ablation. The animals undergoing segmental resection of scar demonstrated no improvement in airway size. Those undergoing total resection experienced a worsening of the condition. Those undergoing microtrapdoor flap repair demonstrated moderate improvement in airway size. It can be concluded that large areas of scar removal in the larynx by the CO2 laser will result in prompt recurrence and possible worsening of the scar and smaller submucosal resection of the scar, with preservation of mucosa by the microtrapdoor flap technique, may be helpful in improving the airway.

摘要

二氧化碳激光作为一种内镜手术器械的引入,激发了人们对其用于去除喉部狭窄病变的兴趣。临床报告表明这种治疗方式的疗效参差不齐。19只大型犬因高速电钻和电灼受到急性声门下损伤。所有动物在受伤后7至21天出现阻塞性病变。通过至少每周一次去除肉芽组织和扩张,所有动物均形成了成熟的声门下和/或后联合瘢痕。两只动物需要气管切开术。实验组的15只动物接受了16次激光手术。三只动物对三分之一的瘢痕进行了汽化,三只对二分之一的瘢痕进行了汽化,三只进行了全周汽化。五只动物接受了微型活板门瓣手术。其中,四只制作了单个瓣膜,一只制作了三个单独的瓣膜。实验组中其余的一只动物形成了声门蹼,已将其完全切除。在一只接受微型活板门瓣手术治疗的动物中,还形成了后窦道,并进行了激光消融治疗。接受瘢痕节段性切除的动物气道大小没有改善。接受全切除的动物病情恶化。接受微型活板门瓣修复的动物气道大小有中度改善。可以得出结论,用二氧化碳激光大面积去除喉部瘢痕会导致瘢痕迅速复发并可能恶化,而采用微型活板门瓣技术保留黏膜对瘢痕进行较小的黏膜下切除可能有助于改善气道。

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