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[类风湿关节炎中接受或未接受金制剂治疗患者的蛋白质清除研究]

[Studies of protein clearance in patients treated with and without gold preparations in rheumatoid arthritis].

作者信息

Gräfenstein K

出版信息

Z Gesamte Inn Med. 1987 Jan 15;42(2):56-8.

PMID:3107230
Abstract

It is reported on investigations of protein clearance in rheumatics treated with Tauredon in comparison to non-treated patients suffering from rheumatoid arthritis. In that way no significant differences concerning the secretion of selective and unselective proteins could be found between the observed groups of patients. Secondary effects of the gold therapy in the form of a relevant proteinuria as elaborated by some authors cannot be confirmed in our patients. On the other hand investigations of protein clearance allow the premature recognition of renal failure and thus they can contribute to the increasing of the patients' security in the application of this therapy.

摘要

据报道,对使用金诺芬治疗的风湿病患者与未治疗的类风湿关节炎患者的蛋白质清除情况进行了调查。通过这种方式,在观察到的患者组之间,未发现选择性和非选择性蛋白质分泌存在显著差异。一些作者阐述的金疗法以相关蛋白尿形式出现的副作用,在我们的患者中无法得到证实。另一方面,蛋白质清除情况的调查有助于早期识别肾衰竭,从而有助于提高患者在应用这种疗法时的安全性。

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