Vlak T, Jajić I
Bolnica za reumatske bolesti i rehabilitaciju, Split.
Reumatizam. 1992;39(2):25-8.
Observing the efficacy of the gold sodium thiomalate (under the trade name of Tauredon Byk Gulden) during the treatment of 43 patients with rheumatoid arthritis, a certain number of side effects have been noted and registered. The group being tested comprised 43 patients, 8 men and 35 women, average age being 50. The side effects were observed in 14 patients (32.5%), namely in one man and 13 woman, the most frequent being thrombocytopenia (20.8%), serious exacerbation of the disease (16.6%), thrombocytosis and dermatitis (12.5%). The recurrence rate of the side effects during the treatment with the gold sodium thiomalate was greater during the first (14%) and the second month (11.8%) than during the third (4.6%) and the fourth month (2.5%).
观察硫代苹果酸金钠(商品名:Tauredon Byk Gulden)治疗43例类风湿性关节炎患者的疗效时,发现并记录了一定数量的副作用。受试组包括43例患者,8名男性和35名女性,平均年龄为50岁。14例患者(32.5%)出现了副作用,其中1名男性和13名女性,最常见的是血小板减少症(20.8%)、疾病严重加重(16.6%)、血小板增多症和皮炎(12.5%)。硫代苹果酸金钠治疗期间副作用的复发率在第一个月(14%)和第二个月(11.8%)高于第三个月(4.6%)和第四个月(2.5%)。