Vlak T, Jajić I
Bolnica za reumatske bolesti i rehabilitaciju, Split.
Reumatizam. 1992;39(2):25-8.
Observing the efficacy of the gold sodium thiomalate (under the trade name of Tauredon Byk Gulden) during the treatment of 43 patients with rheumatoid arthritis, a certain number of side effects have been noted and registered. The group being tested comprised 43 patients, 8 men and 35 women, average age being 50. The side effects were observed in 14 patients (32.5%), namely in one man and 13 woman, the most frequent being thrombocytopenia (20.8%), serious exacerbation of the disease (16.6%), thrombocytosis and dermatitis (12.5%). The recurrence rate of the side effects during the treatment with the gold sodium thiomalate was greater during the first (14%) and the second month (11.8%) than during the third (4.6%) and the fourth month (2.5%).
观察硫代苹果酸金钠（商品名：Tauredon Byk Gulden）治疗43例类风湿性关节炎患者的疗效时，发现并记录了一定数量的副作用。受试组包括43例患者，8名男性和35名女性，平均年龄为50岁。14例患者（32.5%）出现了副作用，其中1名男性和13名女性，最常见的是血小板减少症（20.8%）、疾病严重加重（16.6%）、血小板增多症和皮炎（12.5%）。硫代苹果酸金钠治疗期间副作用的复发率在第一个月（14%）和第二个月（11.8%）高于第三个月（4.6%）和第四个月（2.5%）。
