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[中隔和乳头体的等节律与异节律刺激对家兔脑电图的影响]

[Effect of isorhythmic and heterorhythmic stimulation of the septum and mammillary bodies on the EEG of the rabbit].

作者信息

Korinevskaia I V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jan-Feb;37(1):62-9.

PMID:3107236
Abstract

The influence was studied of combined isorhythmic and heterorhythmic stimulations of the septum and mammillar bodies (S + MB) on spatial organization of brain biopotentials and on the speed of acquisition of defensive conditioned reflex (CR) to light. Analysis of the effect of the isorhythmic stimulation on learning showed that CR elaboration was impeded and in some situations was even impossible. Apparently, isorhythmic S + MB stimulation did not prevent closing of the temporary connection but disturbed CR realization. At simultaneous heterorhythmic electric S + MB stimulations, in most cases cortical parts reproduced only one rhythmic process corresponding to the frequency of the septal stimulation. Combined heterorhythmic S + MB stimulation promoted successful defensive CR elaboration though prolonged action of such stimulations led to development of neurotic state in animals.

摘要

研究了中隔和乳头体的等节律和异节律联合刺激(S + MB)对脑生物电位空间组织以及对光防御性条件反射(CR)习得速度的影响。对等节律刺激对学习的作用分析表明,条件反射的形成受到阻碍,在某些情况下甚至无法形成。显然,等节律的S + MB刺激并未阻止暂时联系的建立,但干扰了条件反射的实现。在同时进行异节律电S + MB刺激时,在大多数情况下,皮层部分仅再现与中隔刺激频率相对应的一个节律过程。异节律S + MB联合刺激促进了防御性条件反射的成功形成,尽管这种刺激的长期作用导致动物出现神经症状态。

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