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[泌尿生殖系统结核组织中分枝杆菌的检测]

[Detection of mycobacteria in tissue in urogenital tuberculosis].

作者信息

Lenk S, Kalich R, Rothkopf M

出版信息

Z Urol Nephrol. 1986 Dec;79(12):709-16.

PMID:3107253
Abstract

121 tissue specimens of the urogenital systems (66 from the kidney, 39 from the epididymis and testis, 8 from the prostate, 4 from the bladder and 4 from the female genital tract) were examined by microscopy, culture and animal experiment on the presence of mycobacteria. In 37 of these specimens (30.6%) mycobacteria were demonstrated, 10 of that only by microscopy and in 27 cases by culture and/or animal experiment. Up to 20 weeks after onset of treatment mycobacteria were demonstrated from the kidney tissue of treated patients by the diagnostic methods mentioned above. After this time mycobacteria never could be demonstrated. There was no correlation between the histological findings and the mycobacteriological investigations. The investigation of tissue specimens on the presence of mycobacteria also from other organs of the urogenital tract is suitable method of the bacteriological proof of tuberculosis, especially in the absence or positive bacteriological findings from the urine or accessory gland secretion for the estimation of species and resistance of these bacteria.

摘要

对121份泌尿生殖系统组织标本(66份来自肾脏,39份来自附睾和睾丸,8份来自前列腺,4份来自膀胱,4份来自女性生殖道)进行了显微镜检查、培养及动物实验,以检测是否存在分枝杆菌。在这些标本中,有37份(30.6%)检测出分枝杆菌,其中10份仅通过显微镜检查发现,27份通过培养和/或动物实验发现。在治疗开始后的20周内,通过上述诊断方法从接受治疗患者的肾脏组织中检测出分枝杆菌。在此之后,再也未能检测出分枝杆菌。组织学检查结果与分枝杆菌学检查之间没有相关性。对泌尿生殖道其他器官的组织标本进行分枝杆菌检测也是结核病细菌学确诊的合适方法,尤其是在尿液或附属腺体分泌物细菌学检查结果为阴性或阳性时,用于评估这些细菌的种类和耐药性。

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