Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, South Korea.
Sci Rep. 2019 May 9;9(1):7158. doi: 10.1038/s41598-019-43585-w.
An association between sleep duration and a wide spectrum of diseases has been reported, but little is known about its relationship with chronic rhinosinusitis (CRS). The present study aimed to investigate whether sleep duration was associated with CRS after adjusting for potential confounding factors in Korean adults. We analyzed data from the Korea National Health and Nutrition Examination Survey 2005-2009 and enrolled 24,658 participants aged ≥20 years. Data regarding sociodemographic characteristics, self-reported sleep duration, CRS, and other medical diseases were collected from questionnaires. Multiple logistic regression analyses were used to identify the relationship between sleep duration and CRS. The overall prevalence of CRS was 4.4%. Subjects with sleep duration ≤5 hours showed a highest prevalence for CRS (6.1%), compared to subjects with longer sleep duration (p = 0.02). After adjusting for covariates (age, sex, household income, residency, dwelling type, education, depression, alcohol, allergic rhinitis, chronic otitis media, angina or myocardial infarction, asthma, chronic obstructive pulmonary disease, bronchiectasis, and gastric ulcer), the sleep duration of ≤5 hours was significantly associated with CRS (OR = 1.502; 95% CI = 1.164-1.938). Only in older subgroup (≥50 years old), shorter sleep duration (≤5 hours) showed higher odds for CRS. These results suggested that sleep duration may be negatively associated with CRS in older Korean adults.
睡眠时长与广泛的疾病存在关联已被报道，但关于其与慢性鼻-鼻窦炎（CRS）的关系知之甚少。本研究旨在调查在调整韩国成年人潜在混杂因素后，睡眠时长与 CRS 之间是否存在关联。我们分析了 2005-2009 年韩国国家健康与营养调查的数据，共纳入 24658 名年龄≥20 岁的参与者。调查问卷收集了社会人口统计学特征、自我报告的睡眠时长、CRS 以及其他医学疾病的数据。采用多因素逻辑回归分析来确定睡眠时长与 CRS 之间的关系。CRS 的总体患病率为 4.4%。与睡眠时长较长的受试者相比（p=0.02），睡眠时长≤5 小时的受试者 CRS 的患病率最高（6.1%）。在调整了协变量（年龄、性别、家庭收入、居住地点、居住类型、教育程度、抑郁、饮酒、变应性鼻炎、慢性中耳炎、心绞痛或心肌梗死、哮喘、慢性阻塞性肺疾病、支气管扩张和胃溃疡）后，睡眠时长≤5 小时与 CRS 显著相关（OR=1.502；95%CI=1.164-1.938）。仅在年龄较大的亚组（≥50 岁）中，较短的睡眠时长（≤5 小时）与 CRS 的发生风险更高相关。这些结果表明，在韩国老年成年人中，睡眠时长可能与 CRS 呈负相关。
