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The current situation of the levonorgestrel intrauterine system (LNG-IUS) in conservative treatment for patients with early-stage endometrial cancer and atypical hyperplasia.左炔诺孕酮宫内节育系统（LNG-IUS）在早期子宫内膜癌和非典型增生患者保守治疗中的现状。
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Mol Clin Oncol. 2023 May 25;19(1):55. doi: 10.3892/mco.2023.2651. eCollection 2023 Jul.
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Fertility issue in early stage endometrial cancer patients.早期子宫内膜癌患者的生育问题。
Transl Cancer Res. 2020 Dec;9(12):7797-7808. doi: 10.21037/tcr-20-2232.
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Contemporary Fertility-Sparing Management Options of Early Stage Endometrioid Endometrial Cancer in Young Nulliparous Patients.年轻未育患者早期子宫内膜样子宫内膜癌的当代保留生育功能管理方案
J Clin Med. 2021 Dec 30;11(1):196. doi: 10.3390/jcm11010196.

本文引用的文献

1
Efficacy and fertility outcomes of levonorgestrel-releasing intra-uterine system treatment for patients with atypical complex hyperplasia or endometrial cancer: a retrospective study.左炔诺孕酮宫内缓释系统治疗非典型复杂性增生或子宫内膜癌患者的疗效和生育结局：一项回顾性研究。
J Gynecol Oncol. 2019 Jul;30(4):e57. doi: 10.3802/jgo.2019.30.e57. Epub 2019 Feb 26.
2
Treatment of Low-Risk Endometrial Cancer and Complex Atypical Hyperplasia With the Levonorgestrel-Releasing Intrauterine Device.左炔诺孕酮宫内节育器治疗低风险子宫内膜癌和复杂性不典型增生
Obstet Gynecol. 2018 Jan;131(1):109-116. doi: 10.1097/AOG.0000000000002390.
3
Gonadotropin-Releasing Hormone Agonist Combined With a Levonorgestrel-Releasing Intrauterine System or Letrozole for Fertility-Preserving Treatment of Endometrial Carcinoma and Complex Atypical Hyperplasia in Young Women.促性腺激素释放激素激动剂联合左炔诺孕酮宫内节育系统或来曲唑用于年轻女性子宫内膜癌和复杂性非典型增生的生育力保留治疗
Int J Gynecol Cancer. 2017 Jul;27(6):1178-1182. doi: 10.1097/IGC.0000000000001008.
4
Combined Oral Medroxyprogesterone/Levonorgestrel-Intrauterine System Treatment for Women With Grade 2 Stage IA Endometrial Cancer.联合口服甲羟孕酮/左炔诺孕酮宫内节育系统治疗Ⅱ级IA期子宫内膜癌女性
Int J Gynecol Cancer. 2017 May;27(4):738-742. doi: 10.1097/IGC.0000000000000927.
5
Oral Progestogens Versus Levonorgestrel-Releasing Intrauterine System for Treatment of Endometrial Intraepithelial Neoplasia<sup/>.口服孕激素与左炔诺孕酮宫内缓释系统治疗子宫内膜上皮内瘤变的比较
J Womens Health (Larchmt). 2017 Apr;26(4):368-373. doi: 10.1089/jwh.2016.5774. Epub 2016 Nov 30.
6
Management of Endometrial Hyperplasia With a Levonorgestrel-Releasing Intrauterine System: A Korean Gynecologic-Oncology Group Study.左炔诺孕酮宫内缓释系统治疗子宫内膜增生：一项韩国妇科肿瘤学组研究
Int J Gynecol Cancer. 2016 May;26(4):711-5. doi: 10.1097/IGC.0000000000000669.
7
Levonorgestrel-releasing intrauterine system vs oral progestins for non-atypical endometrial hyperplasia: a systematic review and metaanalysis of randomized trials.左炔诺孕酮宫内节育系统与口服孕激素治疗非典型子宫内膜增生的比较：一项随机试验的系统评价和荟萃分析
Am J Obstet Gynecol. 2015 Oct;213(4):469-78. doi: 10.1016/j.ajog.2015.03.037. Epub 2015 Mar 19.
8
Progestins in the fertility-sparing treatment and retreatment of patients with primary and recurrent endometrial cancer.孕激素在原发性和复发性子宫内膜癌患者保留生育功能治疗及再次治疗中的应用
Oncologist. 2015 Mar;20(3):270-8. doi: 10.1634/theoncologist.2013-0445. Epub 2015 Feb 11.
9
Long-term oncologic outcomes after fertility-sparing management using oral progestin for young women with endometrial cancer (KGOG 2002).年轻子宫内膜癌患者口服孕激素保留生育功能治疗的长期肿瘤学结局（KGOG 2002）。
Eur J Cancer. 2013 Mar;49(4):868-74. doi: 10.1016/j.ejca.2012.09.017. Epub 2012 Oct 13.
10
Conservative management of young patients with endometrial highly-differentiated adenocarcinoma.年轻子宫内膜高分化腺癌患者的保守治疗
J Obstet Gynaecol. 2011;31(1):13-7. doi: 10.3109/01443615.2010.532249.

The current situation of the levonorgestrel intrauterine system (LNG-IUS) in conservative treatment for patients with early-stage endometrial cancer and atypical hyperplasia.

作者信息

Chen Xiaojun

机构信息

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, China.

出版信息

J Gynecol Oncol. 2019 Jul;30(4):e79. doi: 10.3802/jgo.2019.30.e79. Epub 2019 Apr 1.

DOI:10.3802/jgo.2019.30.e79
PMID:31074232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6543114/
Abstract
摘要