Dagher G
Biochim Biophys Acta. 1987 May 29;899(2):313-6. doi: 10.1016/0005-2736(87)90415-9.
The increase in Ca2+ permeability by addition of ionophore A23187 in the presence of external Ca2+ did not alter the bumetanide-sensitive Na+/K+ effluxes in human red blood cells. An inhibition of this pathway by cellular Ca2+ could be observed only under conditions in which the cellular ATP content was drastically depleted.
在外部钙离子存在的情况下,添加离子载体A23187导致钙离子通透性增加,但并未改变人红细胞中布美他尼敏感的钠钾外流。只有在细胞ATP含量大幅耗尽的条件下,才能观察到细胞内钙离子对该途径的抑制作用。