Freeman David E
Equine Surgery, University of Florida, College of Veterinary Medicine, Large Animal Clinical Sciences, PO Box 100136, Gainesville, FL 32610, USA.
Vet Clin North Am Equine Pract. 2019 Aug;35(2):275-288. doi: 10.1016/j.cveq.2019.03.003. Epub 2019 May 7.
Intravenous lidocaine is widely used to prevent or treat postoperative ileus in horses. Clinical studies that support this approach are flawed and contradicted by others. Also, physical obstruction could be more important in causing postoperative reflux than postoperative ileus in the horse. The antiinflammatory properties of lidocaine and the role of inflammation from intestinal handling in the genesis of postoperative reflux are questionable. Because of cost and questionable efficacy of lidocaine, a well-designed clinical trial is required to support its continued use. However, lidocaine could be given to provide or enhance analgesia in selected cases with postoperative colic.
静脉注射利多卡因被广泛用于预防或治疗马的术后肠梗阻。支持这种方法的临床研究存在缺陷且与其他研究相互矛盾。此外，在导致马术后反流方面，物理性梗阻可能比术后肠梗阻更为重要。利多卡因的抗炎特性以及肠道操作引起的炎症在术后反流发生中的作用值得怀疑。由于利多卡因的成本和疗效存疑，需要进行精心设计的临床试验来支持其继续使用。然而，在某些术后腹痛病例中，可以给予利多卡因以提供或增强镇痛效果。
