Department of Neurosurgery, Sina Hospital, Arad Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of Neurosurgery, Arad Hospital, Tehran University of Medical Sciences, Tehran, Iran.
World Neurosurg. 2019 Aug;128:162-164. doi: 10.1016/j.wneu.2019.04.243. Epub 2019 May 9.
Adenocarcinoma of the salivary gland (AdCASG) is a rare and malignant tumor of the salivary glands. Albeit, metastatic lesions occur anecdotally in the choroid plexus and most rarely in the cerebellopontine angle (CPA). We report the first case of metastatic AdCASG to the choroid plexus of the lateral recess of the fourth ventricle located in CPA, emphasizing the clinical presentation and neuroradiologic findings.
A 40-year-old man was referred with signs of increased intracranial pressure and a unilateral hearing problem. Magnetic resonance imaging showed a pear-shaped, vividly enhancing tumor in the left CPA. The tumor was a metastatic AdCASG. Gross total resection of the lesion was followed by a conventional radiotherapy lead in a 5-year tumor-free control interval.
Metastatic lesions to the choroid plexus may show a pedunculated shape in magnetic resonance imaging. It is hypothesized that tumor seeding may occur through the veins, lymphatics, and nerve sheaths in the skull base region. Tissue specimen is necessary to confirm such rare pathology.
唾液腺癌（AdCASG）是一种罕见的恶性唾液腺肿瘤。尽管如此，转移病灶偶尔会出现在脉络丛，而在小脑脑桥角（CPA）则极为罕见。我们报告首例位于 CPA 第四脑室外侧隐窝的转移性 AdCASG 转移至脉络丛，强调其临床表现和神经影像学表现。
一名 40 岁男性因颅内压增高和单侧听力问题就诊。磁共振成像显示左侧 CPA 呈梨形、明显增强的肿瘤。肿瘤为转移性 AdCASG。病变全切除后，进行了常规放疗，5 年无肿瘤控制期。
磁共振成像显示，转移至脉络丛的病灶可能呈带蒂状。据推测，肿瘤播散可能通过颅底区域的静脉、淋巴管和神经鞘发生。有必要通过组织标本来证实这种罕见的病理学。
