低剂量链激酶溶栓治疗腋-锁骨下静脉血栓形成

Low-dose streptokinase thrombolysis of axillary-subclavian vein thrombosis.

作者信息

Huey H, Morris D C, Nichols D M, Connell D G, Fry P D

出版信息

Cardiovasc Intervent Radiol. 1987;10(2):92-5. doi: 10.1007/BF02577975.

Abstract

Nine patients with 10 episodes of acute axillary-subclavian vein thrombosis were treated with local low-dose streptokinase infusion. All patients except one were heparinized during the procedure with conversion to oral anticoagulation upon completion of the infusion. Recanalization was achieved in 7 patients (70%). Thrombosis recurred in 1, and in 2 patients the procedure was unsuccessful. No major complications were encountered. We concluded that local low-dose streptokinase infusion is a safe, simple, and effective method for treating acute axillary-subclavian vein thrombosis.

摘要

9例发生10次急性腋-锁骨下静脉血栓形成的患者接受了局部小剂量链激酶输注治疗。除1例患者外，所有患者在治疗过程中均接受肝素抗凝，并在输注完成后转换为口服抗凝治疗。7例患者（70%）实现了再通。1例患者血栓复发，2例患者治疗失败。未出现严重并发症。我们得出结论，局部小剂量链激酶输注是治疗急性腋-锁骨下静脉血栓形成的一种安全、简单且有效的方法。