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鼻腔小唾液腺多形性腺瘤一例的磁共振成像与组织病理学

Magnetic Resonance Imaging and Histopathology in a Case of Pleomorphic Adenoma of a Minor Salivary Gland in the Nasal Cavity.

作者信息

Kajiyama Akiko, Edo Hiromi, Inoue Natsuki, Yokouchi Yuki, Gomi Tatsuya

机构信息

Department of Radiology, Toho University Ohashi Medical Center, Tokyo, Japan.

Department of Radiology, Toho University Medical Center, Tokyo, Japan.

出版信息

Am J Case Rep. 2019 May 12;20:679-684. doi: 10.12659/AJCR.915491.

Abstract

BACKGROUND Pleomorphic adenoma of the salivary gland is a common benign tumor of the parotid gland. However, pleomorphic adenoma arising in the minor salivary glands, including the nasopharynx, is uncommon. This report is of a case of nasal pleomorphic adenoma in which the preoperative imaging findings were consistent with the histological features of pleomorphic adenoma of the minor salivary gland, which differs from that of pleomorphic adenoma of the major salivary gland. CASE REPORT A 56-year-old Japanese man was referred to the department of otolaryngology following nasal endoscopy performed at a referral center that identified a right nasal mass. The findings of contrast-enhanced magnetic resonance imaging (MRI) were consistent with a pleomorphic adenoma arising in the nasal septum. Needle biopsy and histology confirmed the diagnosis of pleomorphic adenoma. The tumor was resected using endoscopic surgery, and the histology confirmed the diagnosis of pleomorphic adenoma covered by normal nasal mucosa. CONCLUSIONS This case showed that pleomorphic adenoma arising in the nasal minor salivary gland had typical MRI and histological findings and was a submucosal lesion. Preoperative MRI supported the approach to surgical resection to ensure complete excision.

摘要

背景

涎腺多形性腺瘤是腮腺常见的良性肿瘤。然而,发生于小涎腺(包括鼻咽部)的多形性腺瘤并不常见。本报告介绍了一例鼻腔多形性腺瘤病例,其术前影像学表现与小涎腺多形性腺瘤的组织学特征相符,与大涎腺多形性腺瘤不同。病例报告:一名56岁日本男性在转诊中心接受鼻内镜检查时发现右侧鼻腔肿物,随后被转诊至耳鼻喉科。增强磁共振成像(MRI)结果与鼻中隔发生的多形性腺瘤相符。针吸活检及组织学检查确诊为多形性腺瘤。采用内镜手术切除肿瘤,组织学检查证实为被正常鼻黏膜覆盖的多形性腺瘤。结论:该病例表明,鼻腔小涎腺来源的多形性腺瘤具有典型的MRI及组织学表现,是一种黏膜下病变。术前MRI有助于确定手术切除方案,以确保完整切除肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3ab/6530521/aebb927938fc/amjcaserep-20-679-g001.jpg

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