Division of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah.
Otol Neurotol. 2019 Jun;40(5):e556-e561. doi: 10.1097/MAO.0000000000002199.
To describe the clinical course and treatment outcomes for patients with petrous apex epidermoid with skull base erosion.
Retrospective case series.
Tertiary-care academic center.
Patients surgically managed for petrous apex epidermoids at a single-tertiary care institution from 2001 to 2017.
Surgical management of primary petrous apex epidermoids.
The presenting symptoms, imaging, pre- and postoperative clinical course, and complications were reviewed.
Seven patients were identified. The most common presenting symptoms included: sudden sensorineural hearing loss (n = 3), headaches (n = 1), vertigo (n = 2), and facial paralysis/paresis (n = 2). An epidermoid was discovered in two patients as an incidental finding after a head trauma and one patient after admission for altered mental status and meningitis. Two patients presented with complete facial paralysis (House-Brackmann 6/6). Preoperative normal hearing (pure-tone average < 25 db) was identified in three patients and serviceable hearing (pure-tone average 25-60 dB) in one patient. Three patients with nonserviceable hearing underwent a transcochlear or transotic approach. The remaining four patients underwent an attempted hearing preservation approach. Postoperatively, one patient developed delayed facial paralysis, improving within 3 months. Hearing was preserved in three patients. Two patients developed recurrence of disease within 4 and 7 years respectively.
Surgical management of aggressive petrous apex epidermoid is effective to preserve facial function and prevent recurrence. In our series different surgical approaches were used with variable outcomes.
描述颅底侵蚀性岩尖表皮样瘤患者的临床病程和治疗结果。
回顾性病例系列。
三级保健学术中心。
2001 年至 2017 年期间,在一家三级保健机构接受岩尖表皮样瘤手术治疗的患者。
原发性岩尖表皮样瘤的手术治疗。
回顾了患者的主要症状、影像学表现、术前和术后临床病程以及并发症。
共确定了 7 名患者。最常见的主要症状包括:突发性感音神经性听力损失(n=3)、头痛(n=1)、眩晕(n=2)和面瘫/偏瘫(n=2)。2 名患者因头部外伤后偶然发现,1 名患者因精神状态改变和脑膜炎入院后偶然发现表皮样瘤。2 名患者出现完全性面瘫(House-Brackmann 6/6)。3 名患者术前听力正常(纯音平均<25db),1 名患者可听(纯音平均 25-60db)。3 名听力不可用的患者行经耳蜗或经耳道入路,其余 4 名患者行尝试听力保留入路。术后,1 名患者出现迟发性面瘫,3 个月内恢复。3 名患者听力保留。2 名患者分别在 4 年和 7 年内复发。
岩尖侵袭性表皮样瘤的手术治疗可有效保留面神经功能并预防复发。在我们的系列中,使用了不同的手术方法,结果不同。