• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

原发性岩尖表皮样囊肿伴颅底骨质侵蚀。

Primary Petrous Apex Epidermoids With Skull Base Erosion.

机构信息

Division of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah.

出版信息

Otol Neurotol. 2019 Jun;40(5):e556-e561. doi: 10.1097/MAO.0000000000002199.

DOI:10.1097/MAO.0000000000002199
PMID:31083099
Abstract

OBJECTIVE

To describe the clinical course and treatment outcomes for patients with petrous apex epidermoid with skull base erosion.

STUDY DESIGN

Retrospective case series.

SETTING

Tertiary-care academic center.

PATIENTS

Patients surgically managed for petrous apex epidermoids at a single-tertiary care institution from 2001 to 2017.

INTERVENTIONS

Surgical management of primary petrous apex epidermoids.

MAIN OUTCOME MEASURES

The presenting symptoms, imaging, pre- and postoperative clinical course, and complications were reviewed.

RESULTS

Seven patients were identified. The most common presenting symptoms included: sudden sensorineural hearing loss (n = 3), headaches (n = 1), vertigo (n = 2), and facial paralysis/paresis (n = 2). An epidermoid was discovered in two patients as an incidental finding after a head trauma and one patient after admission for altered mental status and meningitis. Two patients presented with complete facial paralysis (House-Brackmann 6/6). Preoperative normal hearing (pure-tone average < 25 db) was identified in three patients and serviceable hearing (pure-tone average 25-60 dB) in one patient. Three patients with nonserviceable hearing underwent a transcochlear or transotic approach. The remaining four patients underwent an attempted hearing preservation approach. Postoperatively, one patient developed delayed facial paralysis, improving within 3 months. Hearing was preserved in three patients. Two patients developed recurrence of disease within 4 and 7 years respectively.

CONCLUSIONS

Surgical management of aggressive petrous apex epidermoid is effective to preserve facial function and prevent recurrence. In our series different surgical approaches were used with variable outcomes.

摘要

目的

描述颅底侵蚀性岩尖表皮样瘤患者的临床病程和治疗结果。

研究设计

回顾性病例系列。

设置

三级保健学术中心。

患者

2001 年至 2017 年期间,在一家三级保健机构接受岩尖表皮样瘤手术治疗的患者。

干预措施

原发性岩尖表皮样瘤的手术治疗。

主要观察指标

回顾了患者的主要症状、影像学表现、术前和术后临床病程以及并发症。

结果

共确定了 7 名患者。最常见的主要症状包括:突发性感音神经性听力损失(n=3)、头痛(n=1)、眩晕(n=2)和面瘫/偏瘫(n=2)。2 名患者因头部外伤后偶然发现,1 名患者因精神状态改变和脑膜炎入院后偶然发现表皮样瘤。2 名患者出现完全性面瘫(House-Brackmann 6/6)。3 名患者术前听力正常(纯音平均<25db),1 名患者可听(纯音平均 25-60db)。3 名听力不可用的患者行经耳蜗或经耳道入路,其余 4 名患者行尝试听力保留入路。术后,1 名患者出现迟发性面瘫,3 个月内恢复。3 名患者听力保留。2 名患者分别在 4 年和 7 年内复发。

结论

岩尖侵袭性表皮样瘤的手术治疗可有效保留面神经功能并预防复发。在我们的系列中,使用了不同的手术方法,结果不同。

相似文献

1
Primary Petrous Apex Epidermoids With Skull Base Erosion.原发性岩尖表皮样囊肿伴颅底骨质侵蚀。
Otol Neurotol. 2019 Jun;40(5):e556-e561. doi: 10.1097/MAO.0000000000002199.
2
Invasive cerebrospinal fluid cysts and cephaloceles of the petrous apex.岩尖侵袭性脑脊液囊肿和脑膨出。
Otol Neurotol. 2006 Dec;27(8):1131-41. doi: 10.1097/01.mao.0000244353.26954.71.
3
Hearing preservation in management of epidermoids of the cerebellopontine angle: CPA epidermoids and hearing preservation.桥小脑角表皮样瘤的听力保护:CPA 表皮样瘤与听力保护。
Otol Neurotol. 2012 Dec;33(9):1599-603. doi: 10.1097/MAO.0b013e31826bed8d.
4
Management of Petrous Bone Cholesteatoma: The Gruppo Otologico Experience.岩骨胆脂瘤的治疗:Gruppo Otologico 经验。
Eur Arch Otorhinolaryngol. 2024 Oct;281(10):5211-5224. doi: 10.1007/s00405-024-08752-4. Epub 2024 Jun 3.
5
Lateral skull base surgery in a pediatric population: A 25-year experience in a referral skull base center.小儿侧颅底手术:在一家颅底转诊中心的25年经验。
Int J Pediatr Otorhinolaryngol. 2017 Mar;94:70-75. doi: 10.1016/j.ijporl.2017.01.017. Epub 2017 Jan 14.
6
Petrous apex cholesteatoma.岩尖胆脂瘤
Acta Otolaryngol. 2000 Mar;120(2):164-7. doi: 10.1080/000164800750000838.
7
Circumferential petrosectomy for petrous apicitis and cranial base osteomyelitis.用于岩尖炎和颅底骨髓炎的岩骨环形切除术
Otol Neurotol. 2006 Oct;27(7):1003-13. doi: 10.1097/01.mao.0000233811.41177.48.
8
Endoscopic endonasal surgery for petrous apex lesions.经鼻内镜手术治疗岩尖病变。
Laryngoscope. 2009 Jan;119(1):19-25. doi: 10.1002/lary.20027.
9
Surgical Strategy and Facial Nerve Outcomes in Petrous Bone Cholesteatoma.岩骨胆脂瘤的手术策略及面神经预后
Audiol Neurootol. 2016;21(5):275-285. doi: 10.1159/000448584. Epub 2016 Oct 7.
10
The long-term follow-up of drainage procedures for petrous apex cholesterol granulomas.岩尖胆固醇肉芽肿引流手术的长期随访
Arch Otolaryngol Head Neck Surg. 1995 Apr;121(4):426-30. doi: 10.1001/archotol.1995.01890040050008.

引用本文的文献

1
Petrous apex epidermoid cyst: A rare case.岩尖表皮样囊肿:1例罕见病例。
Radiol Case Rep. 2025 Mar 15;20(6):2662-2665. doi: 10.1016/j.radcr.2025.02.047. eCollection 2025 Jun.