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创伤性颈髓损伤后路颈椎减压融合术中脑静脉血栓形成导致脑出血:一例报告

Intracerebral hemorrhage due to cerebral venous thrombosis during posterior cervical decompression and fusion for traumatic cervical cord injury: A case report.

作者信息

Tanaka Kazuya, Yoshida Takashi, Hosoi Kunihiko, Okubo Naoki, Okada Naoya, Hara Yusuke, Kabuto Yukichi, Kubo Toshikazu

机构信息

Department of Orthopaedic Surgery, North Medical Center.

Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Medicine (Baltimore). 2019 May;98(19):e15531. doi: 10.1097/MD.0000000000015531.

DOI:10.1097/MD.0000000000015531
PMID:31083201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6531142/
Abstract

RATIONALE

Cerebral venous thrombosis (CVT) is a cerebrovascular disorder that causes venous infarction and intracerebral hemorrhage (ICH) with occlusion of cerebral veins, and its incidence is estimated to be 5 per 1 million people per year, accounting for 0.5% to 1.0% of all strokes. Despite advances in the recognition of CVT, the diagnosis and treatment may be difficult because of the diversity of underlying risk factors. A rare case of ICH due to CVT during surgery is described.

PATIENT CONCERNS

A 69-year-old-man presented to our department with a history of paralyzed extremities after a backward fall and head trauma. The patient had a history of pharyngeal cancer treated with neck dissection and radiotherapy. Computed tomography (CT) images showed continuous ossification of the posterior longitudinal ligament (OPLL) at C2-5 levels and a fracture line at the caudal end plate of the C5 body. The diagnosis was traumatic cervical cord injury, so that posterior cervical decompression and fusion was performed. Immediately after surgery, the patient developed an epileptic seizure and the disturbance of consciousness persisted. MR venography and contrast CT images showed absence of flow from the superior sagittal sinus to the transverse sinus.

DIAGNOSES

The diagnosis in this case was ICH due to CVT.

INTERVENTIONS

The patient was treated with anticoagulation using unfractionated heparin.

OUTCOMES

The patient ultimately made a complete recovery from CVT.

LESSONS

Although risk factors for CVT are diverse, head and neck injury, patient's position during surgery, and postoperative radical neck dissection for pharyngeal cancer might have been the factors in this case. While the measures to prevent this disease are uncertain, early diagnosis and treatment are needed to avoid serious complications.

摘要

理论依据

脑静脉血栓形成(CVT)是一种脑血管疾病,可导致静脉梗死和脑出血(ICH),伴有脑静脉闭塞,其发病率估计为每年每100万人中有5例,占所有中风的0.5%至1.0%。尽管在CVT的识别方面取得了进展,但由于潜在危险因素的多样性,诊断和治疗可能会很困难。本文描述了一例手术期间因CVT导致ICH的罕见病例。

患者情况

一名69岁男性因向后摔倒和头部外伤后出现肢体瘫痪病史前来我科就诊。该患者有咽癌病史,接受过颈部清扫术和放疗。计算机断层扫描(CT)图像显示C2 - 5水平后纵韧带连续骨化(OPLL)以及C5椎体尾端终板骨折线。诊断为创伤性颈髓损伤,遂行颈椎后路减压融合术。手术后患者立即出现癫痫发作,意识障碍持续存在。磁共振静脉造影和增强CT图像显示上矢状窦至横窦无血流信号。

诊断

本例诊断为CVT导致的ICH。

干预措施

患者接受了普通肝素抗凝治疗。

结果

患者最终从CVT中完全康复。

经验教训

尽管CVT的危险因素多种多样,但头部和颈部损伤、手术期间患者体位以及咽癌术后根治性颈部清扫术可能是本例中的相关因素。虽然预防这种疾病的措施尚不确定,但需要早期诊断和治疗以避免严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/996b/6531142/cae78e805905/medi-98-e15531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/996b/6531142/f852960adc2a/medi-98-e15531-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/996b/6531142/cae78e805905/medi-98-e15531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/996b/6531142/f852960adc2a/medi-98-e15531-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/996b/6531142/b8448bc0cd69/medi-98-e15531-g003.jpg
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