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聚焦禽类病理学:传染性支气管炎病毒。

Spotlight on avian pathology: infectious bronchitis virus.

机构信息

GD Animal Health , Deventer , Netherlands.

Independent scholar.

出版信息

Avian Pathol. 2019 Oct;48(5):393-395. doi: 10.1080/03079457.2019.1617400. Epub 2019 Jun 9.

DOI:10.1080/03079457.2019.1617400
PMID:31084356
Abstract

Infectious bronchitis is a highly infectious disease of the domestic chicken of all ages and type, affecting the respiratory, renal and reproductive systems. Secondary bacterial infections are common and have a serious economic and welfare impact. Many genotypic and serotypic variants of infectious bronchitis virus (IBV) exist worldwide, making diagnosis difficult, and challenging control strategies. Vaccination, requiring the use of both live-attenuated and inactivated vaccines, is needed to control IBV infections; to date, attempts to develop vectored vaccines as effective as the traditional vaccines have been unsuccessful.

摘要

传染性支气管炎是一种高度传染性疾病,可影响所有年龄和品种的家禽的呼吸道、肾脏和生殖系统。常见继发细菌性感染,对经济和福利有严重影响。传染性支气管炎病毒(IBV)在世界范围内存在许多基因型和血清型变异,使得诊断变得困难,并对控制策略构成挑战。需要使用活疫苗和灭活疫苗来控制 IBV 感染,接种疫苗;迄今为止,试图开发与传统疫苗一样有效的载体疫苗的尝试都没有成功。

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