Seval Guldane Cengiz, Ozkan Elgin, Beksac Meral
Department of Hematology, Ankara University School of Medicine, Cebeci Research and Application Hospital, Mamak, Amkara 06590, Turkey.
Department of Nuclear Medicine, Ankara University School of Medicine, Cebeci Research and Application Hospital, Mamak, Amkara 06590, Turkey.
PET Clin. 2019 Jul;14(3):369-381. doi: 10.1016/j.cpet.2019.03.009. Epub 2019 Apr 12.
In the past decade novel treatment options have dramatically prolonged the survival of patients with multiple myeloma. PET combined with computed tomography (CT) is a sensitive and reliable functional imaging tool that enables diagnosis and assessment of response to chemotherapy/radiotherapy, and combines high sensitivity in identifying both lytic lesions and extramedullary soft-tissue masses with the ability to provide reliable prognostic information in the management of patients with myeloma. This review comprises a comprehensive overview of PET with fluorodeoxyglucose F 18/CT imaging in combination with other convenient imaging procedures, and attempts at standardization with emphasis on post-therapy findings in patients with myeloma.
在过去十年中，新型治疗方案显著延长了多发性骨髓瘤患者的生存期。正电子发射断层显像（PET）与计算机断层扫描（CT）相结合是一种敏感且可靠的功能成像工具，可用于诊断及评估化疗/放疗反应，它在识别溶骨性病变和髓外软组织肿块方面具有高敏感性，同时能够在骨髓瘤患者管理中提供可靠的预后信息。本综述全面概述了氟代脱氧葡萄糖F 18/CT成像的PET与其他便捷成像程序的联合应用，并尝试进行标准化，重点关注骨髓瘤患者的治疗后表现。
