Kanner R S, Tedesco F J, Kalser M H
Am J Dig Dis. 1978 Oct;23(10):956-8. doi: 10.1007/BF01072475.
A patient with Azulfidine-related hepatotoxicity in which prompt recurrence of symptoms, fever skin rash, and laboratory evidence of hepatocellular injury occurred upon readministration of Azulfidine is reported. The clinical and biochemical features support the fact that this was an example of an acquired hypersensitivity reaction to Azulfidine.
据报道,有一名服用柳氮磺胺吡啶后出现肝毒性的患者,再次服用柳氮磺胺吡啶后症状迅速复发、出现发热皮疹以及肝细胞损伤的实验室证据。临床和生化特征支持这是对柳氮磺胺吡啶获得性过敏反应的一个实例。