Mughal M M, Meguid M M
JPEN J Parenter Enteral Nutr. 1987 Mar-Apr;11(2):140-3. doi: 10.1177/0148607187011002140.
The effect of nutritional status on the morbidity and mortality of major gastrointestinal surgery for benign disease was studied in 32 patients. Malnutrition was defined as a serum albumin less than 3.5 g/dl and a recent weight loss greater than 10%, in addition to any two of the following: weight for height, midarm circumference or triceps skin-fold thickness less than 10th percentile. The morbidity and mortality in the 17 malnourished patients was 59% and 29%, respectively, compared with 20% and 7% in 15 well-nourished patients matched for age and operative procedure (p less than 0.05). After operation, the mean duration of inadequate oral nutritional intake period (IONIP, defined as a caloric intake greater than 60% requirement) was 11.9 days +/- 2.9 (SEM) in well-nourished patients compared with 30.5 days +/- 3.7 in the malnourished group. The longer IONIP in malnourished patients was a consequence of the higher morbidity in this group, thus warranting the consideration of supportive (postoperative) parenteral nutrition in malnourished patients who undergo major gastrointestinal surgery for benign disease.
对32例患者研究了营养状况对良性疾病胃肠大手术发病率和死亡率的影响。营养不良的定义为血清白蛋白低于3.5g/dl、近期体重减轻超过10%，此外还有以下任意两项：身高体重、上臂中部周长或三头肌皮褶厚度低于第10百分位数。17例营养不良患者的发病率和死亡率分别为59%和29%，而15例年龄和手术方式匹配的营养良好患者的发病率和死亡率分别为20%和7%（p<0.05）。术后，营养良好患者口服营养摄入不足期（IONIP，定义为热量摄入大于需求的60%）的平均持续时间为11.9天±2.9（标准误），而营养不良组为30.5天±3.7。营养不良患者IONIP较长是该组较高发病率的结果，因此对于接受良性疾病胃肠大手术的营养不良患者，有必要考虑给予支持性（术后）肠外营养。
