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细针穿刺抽吸活检(FNAC)及其在孤立性甲状腺结节中的应用及其与组织病理学检查的相关性。

FNAC and Its Utility in Solitary Thyroid Nodule and Its Correlation with Histopathological Examination.

作者信息

Momin M A, Bhuiyan F U, Chakraborty S, Kar N K

机构信息

Dr Md Abdul Momin, Assistant Professor, Department of Surgery, Mainamoti Medical College, Cumilla, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2019 Apr;28(2):356-363.

Abstract

Discrete swelling in one lobe of thyroid gland with no palpable abnormality elsewhere is termed as a solitary thyroid nodule. FNAC is the investigation of choice in solitary nodule for selection of surgical cases due to compliance, simple and quick to perform. The aim of this study was to evaluate the utility of FNAC in solitary thyroid nodule with the relation of histopathological findings. In this prospective observational study fifty (50) patients of solitary thyroid nodule without multinodular goitre, diffuse goitre, dominant nodule and clinically hypothyroidism or hyperthyroidism were included from admitted patients of different institutes of Comilla both private and government Medical College Hospital, Bangladesh. All patients were clinically examined and investigation findings from thyroid scan, ultrasonogram of thyroid gland, FNAC of thyroid nodule, histopathological report of excised thyroid were collected and posted into data collection sheet. The data were analysed with simple statistical table. The result showed that among 50 patients 41 patients were detected as benign nodule after FNAC which is about 82%. Malignant lesions were 12% (6 patients) and 6% (3 patients) of the case was indeterminate as because the specimen were unsatisfactory. The sensitivity, specificity, and accuracy of FNAC diagnosis in relation to histopathological findings were 100%, 83.33% and 97.87%. So FNAC is sensitive and accurate method for evaluation of solitary thyroid nodules.

摘要

甲状腺一个叶出现离散性肿胀,而其他部位未触及异常,称为甲状腺单发结节。由于操作依从性好、简单快捷,细针穿刺抽吸活检(FNAC)是甲状腺单发结节手术病例选择的首选检查方法。本研究旨在评估FNAC在甲状腺单发结节中的应用价值及其与组织病理学结果的关系。在这项前瞻性观察研究中,从孟加拉国科米拉不同私立和政府医学院附属医院的住院患者中纳入了50例无多结节性甲状腺肿、弥漫性甲状腺肿、优势结节且临床无甲状腺功能减退或亢进的甲状腺单发结节患者。对所有患者进行临床检查,并收集甲状腺扫描、甲状腺超声检查、甲状腺结节FNAC、切除甲状腺的组织病理学报告等检查结果,记录在数据收集表中。数据采用简单统计表进行分析。结果显示,50例患者中,FNAC检查后41例被诊断为良性结节,约占82%。恶性病变占12%(6例),6%(3例)病例结果不确定,原因是标本不理想。FNAC诊断相对于组织病理学结果的敏感性、特异性和准确性分别为100%、83.33%和97.87%。因此,FNAC是评估甲状腺单发结节的敏感且准确的方法。

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