Tuli J Z, Chakraborty P K, Hoque M R, Sarkar S, Rahman M M, Begum S, Alam M T
Dr Jesmin Zahan Tuli, Lecturer, Department of Biochemistry, Sheikh Hasina Medical College, Jamalpur, Bangladesh; E-mail:
Mymensingh Med J. 2019 Apr;28(2):429-433.
Preeclampsia is one of the most frequent complication of pregnancy which manifested by hypertension during pregnancy for the first time after 20th weeks of gestation with proteinuria. The aim of the study was to estimate the changes in serum calcium level in preeclamptic patients when compared with normal pregnant women. The case control study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, Bangladesh in collaboration with the Department of Obstetrics and Gynecology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from July 2016 to June 2017. A total of 100 subjects were included. Among them 50 were subjects of preeclamptic patients as case and another 50 were apparently healthy normal pregnant women as control. The study revealed that serum calcium level was lower in preeclamptic women (case) as compared to healthy control subjects. The mean values of serum calcium levels were 7.63±0.42 and 8.12±0.94mg/dl in case and control group respectively. The difference in mean serum calcium were highly significant (p<0.001) when compared between case and control.
子痫前期是妊娠最常见的并发症之一，其表现为妊娠20周后首次出现高血压并伴有蛋白尿。本研究的目的是评估子痫前期患者与正常孕妇相比血清钙水平的变化。2016年7月至2017年6月，在孟加拉国迈门辛市迈门辛医学院生物化学系与迈门辛医学院医院妇产科合作开展了这项病例对照研究。共纳入100名受试者。其中50名是子痫前期患者作为病例组，另外50名是明显健康的正常孕妇作为对照组。研究显示，子痫前期女性（病例组）的血清钙水平低于健康对照组。病例组和对照组血清钙水平的平均值分别为7.63±0.42mg/dl和8.12±0.94mg/dl。病例组和对照组之间平均血清钙的差异非常显著（p<0.001）。
