三维可视化系统引导下的微波消融治疗复发性肝母细胞瘤的小样本初步研究。
Microwave ablation assisted by three-dimensional visualization system as local therapy for relapsed hepatoblastoma: a small pilot study.
机构信息
Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Department of Laser Medicine, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
出版信息
Abdom Radiol (NY). 2019 Aug;44(8):2909-2915. doi: 10.1007/s00261-019-02011-5.
PURPOSE
We aimed to explore the feasibility of microwave ablation (MWA) assisted by three-dimensional visualization system for relapsed HB in children.
METHODS
From August 2014 to February 2017, five patients with relapsed HB were enrolled. A total of 12 liver tumors were treated with MWA assisted by a three-dimensional visualization system. Follow-up data were obtained in all patients. The residual liver volume, local tumor progression, new intrahepatic tumors, survival outcome, and complications were analyzed.
RESULTS
All tumors were completely ablated in a single session. The mean ablation time per tumor was 9.7 ± 8.6 min, and the median ablation/liver volume ratio was 2.37%. No local tumor progression was observed during a follow-up period of 9-39 months. All patients were still alive at the end of the follow-up. The median progression-free survival time after ablation was 9 months, and the median survival time after ablation was 12 months. No other complications were observed except for fever.
CONCLUSIONS
MWA assisted by three-dimensional visualization system appears to be a safe and feasible local treatment for recurrent HB in pediatric patients.
目的
本研究旨在探讨三维可视化系统辅助下微波消融（MWA）治疗儿童复发性肝母细胞瘤（HB）的可行性。
方法
2014 年 8 月至 2017 年 2 月，5 例复发性 HB 患儿纳入研究。共对 12 个肝肿瘤行三维可视化系统辅助下 MWA 治疗。所有患者均获得随访，分析其残肝体积、局部肿瘤进展、新的肝内肿瘤、生存结局及并发症等情况。
结果
所有肿瘤均在单次治疗中完全消融。每个肿瘤的平均消融时间为 9.7±8.6 min，平均消融/肝体积比为 2.37%。随访 9~39 个月，无局部肿瘤进展。随访结束时，所有患者均存活。消融后无进展生存时间的中位数为 9 个月，消融后总生存时间的中位数为 12 个月。除发热外，无其他并发症发生。
结论
三维可视化系统辅助 MWA 治疗儿童复发性 HB 是一种安全、可行的局部治疗方法。
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