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Opioid: toward an effective strategy for better use.阿片类药物：迈向更好使用的有效策略。
Korean J Pain. 2019 Apr 1;32(2):67-68. doi: 10.3344/kjp.2019.32.2.67.
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Biased Agonism as an Emerging Strategy in the Search for Better Opioid Analgesics.在寻找更好的阿片类镇痛药的过程中，偏激动剂作为一种新兴策略。
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Innovative Opioid Peptides and Biased Agonism: Novel Avenues for More Effective and Safer Analgesics to Treat Chronic Pain.创新型阿片肽和偏向激动剂：用于治疗慢性疼痛的更有效和更安全的镇痛药的新途径。
Curr Med Chem. 2018;25(32):3895-3916. doi: 10.2174/0929867324666170216095233.
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Progress in the development of more effective and safer analgesics for pain management.疼痛管理中更有效和更安全的镇痛药的发展进展。
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Mu- and delta-opioid receptors inhibitorily linked to dopamine-sensitive adenylate cyclase in rat striatum display a selectivity profile toward endogenous opioid peptides different from that of presynaptic mu, delta and kappa receptors.在大鼠纹状体中，与多巴胺敏感的腺苷酸环化酶呈抑制性连接的μ和δ阿片受体，对内源性阿片肽的选择性谱不同于突触前μ、δ和κ受体。
J Pharmacol Exp Ther. 1993 Oct;267(1):205-10.
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Knowledge of Opioid Overdose and Attitudes to Supply of Take-Home Naloxone Among People with Chronic Noncancer Pain Prescribed Opioids.慢性非癌症疼痛患者对阿片类药物处方知识、阿片类药物过量及携带纳洛酮的态度。
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Social Stigma Toward Persons With Prescription Opioid Use Disorder: Associations With Public Support for Punitive and Public Health-Oriented Policies.对患有处方阿片类药物使用障碍者的社会污名：与公众对惩罚性政策和公共卫生导向政策支持的关联。
Psychiatr Serv. 2017 May 1;68(5):462-469. doi: 10.1176/appi.ps.201600056. Epub 2017 Jan 3.
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A randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care.一项系统咨询的可行性、可接受性和有效性的随机匹配对研究：一种在初级保健中采用阿片类药物处方临床指南的新型实施策略。
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p38 Mitogen-activated protein kinase activation by nerve growth factor in primary sensory neurons upregulates μ-opioid receptors to enhance opioid responsiveness toward better pain control.p38 丝裂原活化蛋白激酶在初级感觉神经元中被神经生长因子激活，上调μ-阿片受体，增强阿片类药物的反应性，从而更好地控制疼痛。
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SCOPE of Pain: An Evaluation of an Opioid Risk Evaluation and Mitigation Strategy Continuing Education Program.疼痛范围：阿片类药物风险评估与缓解策略继续教育项目评估
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Effect of Intranasal Ketamine on Pain Intensity after Cesarean Section: A Single-Center, Double Blind, Randomized Controlled Trial.鼻腔内给予氯胺酮对剖宫产术后疼痛强度的影响：一项单中心、双盲、随机对照试验。
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Medicolegal Consideration to Prevent Medical Malpractice Regarding Opioid Administration: An Analysis of Judicial Opinion in South Korea.预防阿片类药物给药医疗事故的法医学考量：韩国司法意见分析
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Patients' perception about opioids and addiction in South Korea.韩国患者对阿片类药物和成瘾的认知
Korean J Pain. 2020 Jul 1;33(3):234-244. doi: 10.3344/kjp.2020.33.3.234.

本文引用的文献

1
Opioid-induced constipation: a narrative review of therapeutic options in clinical management.阿片类药物引起的便秘：临床管理中治疗选择的叙述性综述
Korean J Pain. 2019 Apr 1;32(2):69-78. doi: 10.3344/kjp.2019.32.2.69.
2
Guidelines for prescribing opioids for chronic non-cancer pain in Korea.韩国慢性非癌性疼痛阿片类药物处方指南。
Korean J Pain. 2017 Jan;30(1):18-33. doi: 10.3344/kjp.2017.30.1.18. Epub 2016 Dec 30.
3
Long-term opioid management for chronic noncancer pain.慢性非癌性疼痛的长期阿片类药物管理
Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD006605. doi: 10.1002/14651858.CD006605.pub2.
4
What do different databases tell about the use of opioids in seven European countries in 2002?不同的数据库对2002年七个欧洲国家阿片类药物的使用情况有何说明？
Eur J Pain. 2008 Aug;12(6):705-15. doi: 10.1016/j.ejpain.2007.10.012. Epub 2007 Dec 26.
5
Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids.慢性非恶性疼痛中阿片类药物不良事件的患病率：口服阿片类药物随机试验的系统评价
Arthritis Res Ther. 2005;7(5):R1046-51. doi: 10.1186/ar1782. Epub 2005 Jun 28.
6
Persistent pain as a disease entity: implications for clinical management.持续性疼痛作为一种疾病实体：对临床管理的影响。
Anesth Analg. 2004 Aug;99(2):510-20, table of contents. doi: 10.1213/01.ANE.0000133383.17666.3A.
7
Recommendations for using opioids in chronic non-cancer pain.慢性非癌性疼痛中使用阿片类药物的建议。
Eur J Pain. 2003;7(5):381-6. doi: 10.1016/S1090-3801(02)00143-X.
8
The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society.阿片类药物用于慢性疼痛治疗。美国疼痛医学学会和美国疼痛学会的共识声明。
Clin J Pain. 1997 Mar;13(1):6-8.
9
Randomised trial of oral morphine for chronic non-cancer pain.口服吗啡治疗慢性非癌性疼痛的随机试验。
Lancet. 1996 Jan 20;347(8995):143-7. doi: 10.1016/s0140-6736(96)90339-6.
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The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation.
JAMA. 1995 Dec 20;274(23):1870-3.

Opioid: toward an effective strategy for better use.

作者信息

Kim Yeon-Dong

出版信息

Korean J Pain. 2019 Apr 1;32(2):67-68. doi: 10.3344/kjp.2019.32.2.67.

DOI:10.3344/kjp.2019.32.2.67
PMID:31091504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6549590/
Abstract
摘要