Salomon N W, Copeland J G, Goldman S, Larson D F
J Thorac Cardiovasc Surg. 1979 Feb;77(2):294-6.
A 65-year-old man underwent aortic valve replacement and triple coronary artery bypass grafting which were followed by gradual late postoperative thrombosis of his 25 mm. Hancock porcine aortic heterograft. At reoperation, the valve struts were noted to be angled centrally into the aortic lumen and dense thrombus completely filled all three sinuses. After valve removal and extensive debridement of the aortic anulus, including relaxing incisions, a diameter of only 23 mm. was obtained. A 23 mm. Björk-Shiley aortic prosthesis was inserted and the patient's recovery was uneventful. This previously unreported complication resulted from the insertion of a too-large Hancock porcine heterograft into a relatively small aortic root, resulting in circumferential strut compression, impedance of central flow, and subsequent valve thrombosis.
一名65岁男性接受了主动脉瓣置换术和三支冠状动脉搭桥术，术后其25毫米的汉考克猪主动脉异种移植瓣膜逐渐出现晚期血栓形成。再次手术时，发现瓣膜支柱向主动脉腔中心成角，致密血栓完全充满了所有三个窦。在移除瓣膜并对主动脉瓣环进行广泛清创，包括松弛切口后，仅获得了23毫米的直径。植入了一个23毫米的比约克-希利主动脉假体，患者恢复顺利。这种先前未报道的并发症是由于将过大的汉考克猪异种移植瓣膜植入相对较小的主动脉根部，导致周向支柱受压、中心血流受阻以及随后的瓣膜血栓形成。
