Högman C F, De Verdier C H, Eriksson L, Sandhagen B
Biomed Biochim Acta. 1987;46(2-3):S290-4.
When red cells are stored in plastic (PVC) containers the penetration of blood gases--O2 entering into and CO2 escaping out of the blood units--influences the red cell metabolism; ATP and energy charge are better maintained at anaerobic storage. When sedimented cells are stored unmixed, the blood gas diffusion is markedly restricted and the concentration of metabolites is rapidly increasing. This leads to disturbed metabolism, increased microvesiculation and decreased erythrocyte fluidity. In a blood transfusion service producing blood components, this is likely to have an important impact on the quality of the red cells. It seems advisable to store red cells in a sufficiently large volume of a suspension medium (such as the SAGM solution) and apply mixing during storage.
当红细胞储存在塑料（聚氯乙烯）容器中时，血气的渗透——氧气进入血液单位以及二氧化碳从血液单位逸出——会影响红细胞代谢；在无氧储存条件下，三磷酸腺苷（ATP）和能荷能得到更好的维持。当沉降的细胞未经混合储存时，血气扩散会受到显著限制，代谢产物的浓度会迅速增加。这会导致代谢紊乱、微囊泡化增加以及红细胞流动性降低。在生产血液成分的输血服务机构中，这可能会对红细胞质量产生重要影响。将红细胞储存在足够大量的悬浮介质（如SAGM溶液）中并在储存期间进行混合似乎是可取的。
