Parfеnov А I, Аkopova А О, Shcherbakov P L, Мikcheeva О М
A.S. Loginov Moscow Clinical Research and Practical Center of the Department of Health of Moscow, Moscow, Russia.
Clinical and Diagnostical Center MEDSI on Krasnaya Presnya, Moscow, Russia.
Ter Arkh. 2019 May 16;91(4):37-42. doi: 10.26442/00403660.2019.04.000079.
To evaluate the possibilities of video capsule endoscopy (VCE) for diagnosing small bowel Crohn's disease (SBCD).
The study included 25 patients (12 men, 13 women) diagnosed with Crohn's disease. The mean age of the patients was 31.84±10.5 years. The VCE was performed using the GivenImaging system (Yokneam, Israel), OMOM (China). After the end of each test, the data was analyzed at a rate of 8 to 10 frames per second using Rapid® Reader (version 7.0).
The examination of patients in accordance with the diagnostic algorithm showed that for 11 patients (44%) the clinical assumption of SBCD was confirmed only with the help of VCE (1st group). Consequently, the use of VCE in these patients was crucial in the diagnosis of SBCD, since standard methods of analisys were insufficient to establish this diagnosis. For 14 patients (2nd group), the diagnosis of SBCD was established with the help of colonoscopy and/or diagnostic imaging modalities. The use of VCE allowed to confirm the diagnosis, to clarify the localization and extent of inflammation of the small intestine.
VCE can be recommended for the diagnosis of SBCD during the period of early inflammatory manifestations in the small intestine mucosa.
评估视频胶囊内镜（VCE）诊断小肠克罗恩病（SBCD）的可能性。
本研究纳入25例诊断为克罗恩病的患者（12例男性，13例女性）。患者的平均年龄为31.84±10.5岁。使用以色列Given Imaging公司的GivenImaging系统、中国的OMOM进行VCE检查。每次检查结束后，使用Rapid® Reader（7.0版）以每秒8至10帧的速率对数据进行分析。
按照诊断算法对患者进行检查显示，对于11例患者（44%），仅借助VCE才证实了SBCD的临床推测（第1组）。因此，在这些患者中使用VCE对SBCD的诊断至关重要，因为标准分析方法不足以确立该诊断。对于14例患者（第2组），借助结肠镜检查和/或诊断成像方式确立了SBCD的诊断。使用VCE能够证实诊断，明确小肠炎症的定位和范围。
在小肠黏膜早期炎症表现期，VCE可推荐用于SBCD的诊断。
