Cho Kyoung Hee, Nam Chung Mo, Lee Sang Gyu, Kim Tae Hyun, Lee Seon-Heui, Park Eun-Cheol
Department of Public Health, Graduate School.
Institute of Health Services Research, College of Medicine.
Medicine (Baltimore). 2019 May;98(20):e15353. doi: 10.1097/MD.0000000000015353.
Ischemic stroke, hemorrhagic stroke, and acute myocardial infarction (AMI) are diseases with golden hour. This study aimed to identify and compare factors that affect in-hospital mortality in patients with stroke and AMI who admitted via the emergency department.This study used the Korean National Health Insurance claims data from 2002 to 2013. The study sample included 7693 patients who had an ischemic stroke, 2828 patients who had a hemorrhagic stroke, and 4916 patients with AMI who were admitted via the emergency departments of a superior general hospital and general hospital, did not transfer to another hospital or come from another hospital, and were aged ≥20 years. This study was analyzed by using Cox's proportional hazards frailty model.Five hundred (6.5%) of 7693 patients with ischemic stroke, 569 (20.1%) of 2828 patients with hemorrhagic stroke, and 399 (8.1%) of 4916 patients with AMI were dead. The clinical factors were associated with in-hospital mortality such as age, CCI, hypertension, and diabetes of patient characteristics. In treatment characteristics, performing PCI and weekday admission was associated with in-hospital mortality (aHR, 0.43; 95% CI, 0.27-0.67; aHR, 1.42; 95% CI, 1.14-1.77, respectively). In hospital characteristics, the volume, the proportion of transferred patient to other hospital and ratio of beds per one nurse was associated with in-hospital mortality.Clinical factors of patient characteristics, intervention such as performing PCI and reducing ICP of treatment characteristics, and the volume, transferred rate, and the number of nurse of hospital characteristics were associated with in-hospital mortality.
缺血性中风、出血性中风和急性心肌梗死(AMI)都是具有黄金救治时间的疾病。本研究旨在识别并比较经急诊科收治的中风和AMI患者住院死亡率的影响因素。本研究使用了2002年至2013年韩国国民健康保险索赔数据。研究样本包括7693例缺血性中风患者、2828例出血性中风患者以及4916例AMI患者,这些患者均通过一家上级综合医院和综合医院的急诊科收治,未转至其他医院或来自其他医院,且年龄≥20岁。本研究采用Cox比例风险脆弱模型进行分析。7693例缺血性中风患者中有500例(6.5%)死亡,2828例出血性中风患者中有569例(20.1%)死亡,4916例AMI患者中有399例(8.1%)死亡。临床因素与住院死亡率相关,如患者特征中的年龄、Charlson合并症指数(CCI)、高血压和糖尿病。在治疗特征方面,进行经皮冠状动脉介入治疗(PCI)和工作日入院与住院死亡率相关(风险比[aHR]分别为0.43;95%置信区间[CI]为0.27 - 0.67;aHR为1.42;95% CI为1.14 - 1.77)。在医院特征方面,医院规模、转至其他医院的患者比例以及每护士床位比与住院死亡率相关。患者特征的临床因素、PCI等治疗干预措施以及治疗特征中的降低颅内压、医院特征中的医院规模、转院率和护士数量与住院死亡率相关。