Callam M J, Harper D R, Dale J J, Ruckley C V
Br Med J (Clin Res Ed). 1987 May 30;294(6584):1389-91. doi: 10.1136/bmj.294.6584.1389.
Six hundred patients with chronic leg ulcers were studied by detailed history and examination as part of a population survey. In 22% ulceration began before the age of 40, and in this group the sex incidence was equal. Over age 40 there was an increasing preponderance of women. Ulcers were significantly more common in the left leg in women but not in men. The site of 26% of ulcers did not include the classical medial goiter area. The median duration of the ulceration at the time of the survey was nine months and 20% had not healed in over two years. The great majority of patients had had recurrence, 66% having had episodes of ulceration for more than five years. Healing of ulcers is a serious problem, but preventing recurrence is the greater challenge.
作为一项人群调查的一部分,对600例慢性腿部溃疡患者进行了详细的病史询问和检查。22%的患者在40岁之前开始出现溃疡,该组的性别发病率相同。40岁以上女性的比例逐渐增加。溃疡在女性左腿明显更常见,而在男性中并非如此。26%的溃疡部位不包括经典的内侧甲状腺肿区域。调查时溃疡的中位持续时间为9个月,20%的患者在两年多未愈合。绝大多数患者有复发,66%的患者有超过五年的溃疡发作史。溃疡愈合是一个严重的问题,但预防复发是更大的挑战。