Center for Communicable Disease Research, Institute for Public Health, Malaysia, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
Environmental Health Institute, (WHO Collaboration Center for Reference and Research of Arbovirus and Their Associated Vectors) National Environment Agency, Singapore, Singapore, Singapore.
BMJ Open. 2019 May 15;9(5):e026101. doi: 10.1136/bmjopen-2018-026101.
Dengue is among the most important mosquito-borne diseases, with more than half of the world's population at risk of infection in dengue endemic countries. Environmental management, which includes any activities that involve environmental modification, environmental manipulation and changes to human behaviour have been used to mitigate the risk of dengue transmission. In this protocol, we will integrate the data from various sources to assess the overall effect of environmental management on the incidence of dengue and other entomological indices.
We will conduct a systematic review of intervention that assess the effect of environmental management on the incidence of dengue and/or entomological indices. We will include any studies that include intervention through environmental management for dengue control, involving environmental modification, environmental manipulation and changes to human behaviour. A comprehensive search will be performed in electronic databases PUBMED, CENTRAL, SCOPUS, Web of Science and relevant research websites such as PROPSERO, WHO ICTRP and ClinicalTrials.gov to identify studies that meet our inclusion criteria. A systematic approach to searching, screening, reviewing and data extraction will be applied based on Preferred Reporting Items for Systematic reviews and Meta-Analysis. Titles, abstract, keywords for eligibility will be examined independently by researchers. The quality of the included studies will be assessed using quality assessment tool for studies with diverse design and Cochrane risk of bias tool. The characteristics of the selected articles will be described based on the study design, types of intervention and outcomes of the study in various countries. These include the types of environmental management intervention methods and the effectiveness of the intervention in reducing dengue cases or incidence and impact on entomological indices.
We will register this systematic review with the National Medical Research Register, Ministry of Health Malaysia. This protocol also had been registered with the PROSPERO. No ethical approval is necessary, as there will be no collection of primary data. The results will be disseminated though a peer-reviewed publication and conference presentation.
CRD42018092189.
登革热是最重要的蚊媒传染病之一，在登革热流行国家，超过一半的世界人口面临感染风险。环境管理包括任何涉及环境改造、环境操纵和改变人类行为的活动，已被用于降低登革热传播的风险。在本方案中，我们将整合来自不同来源的数据，以评估环境管理对登革热发病率和其他昆虫学指标的总体影响。
我们将对评估环境管理对登革热发病率和/或昆虫学指标影响的干预措施进行系统评价。我们将包括任何通过环境管理进行的干预措施，以控制登革热，包括环境改造、环境操纵和改变人类行为。将在电子数据库 PUBMED、CENTRAL、SCOPUS、Web of Science 和相关研究网站（如 PROPSERO、WHO ICTRP 和 ClinicalTrials.gov）中进行全面搜索，以确定符合纳入标准的研究。将根据系统评价和荟萃分析的首选报告项目，采用系统的搜索、筛选、审查和数据提取方法。研究人员将独立检查标题、摘要和关键词的资格。将使用不同设计的研究质量评估工具和 Cochrane 偏倚风险工具评估纳入研究的质量。将根据研究设计、干预类型和不同国家研究的结果，描述选定文章的特征。这些包括环境管理干预方法的类型和干预在减少登革热病例或发病率方面的有效性，以及对昆虫学指标的影响。
我们将在马来西亚卫生部国家医学研究登记处注册本系统评价。本方案也已在 PROSPERO 注册。由于不收集原始数据，因此不需要伦理批准。结果将通过同行评议的出版物和会议演示进行传播。
CRD42018092189。
