Malvisi Stracciari J, Venturini A P, Anfossi P, Marchi E, Stracciari G L
Chemioterapia. 1987 Apr;6(2):82-4.
The in vitro sensitivity of the H 37 RV strain of Mycobacterium tuberculosis to rifaximin and rifampicin was determined by evaluating both the antimycobacterial activity of the two rifamycin derivatives after oral administration to infected guinea pigs and the influence of rifaximin on the susceptibility to rifampicin of the isolated strain from spleen, lungs and liver. The results showed that after oral treatment with rifaximin no changes regarding the sensitivity of the strain to rifaximin and rifampicin were seen.
通过评估两种利福霉素衍生物经口给予感染豚鼠后的抗分枝杆菌活性以及利福昔明对从脾脏、肺和肝脏分离菌株对利福平敏感性的影响，测定了结核分枝杆菌H 37 RV菌株的体外敏感性。结果显示，经利福昔明口服治疗后，该菌株对利福昔明和利福平的敏感性未见变化。
