关于1,2,3 - 三唑衍生物作为环氧化酶潜在抑制剂的研究。
Studies on 1,2,3-triazole derivatives as potential inhibitors of the cyclo-oxygenase.
作者信息
Biagi G, Livi O, Scartoni V
出版信息
Farmaco Sci. 1987 Apr;42(4):285-97.
PMID:3109939
Abstract
A number of novel alpha-[4-substituted-(1,2,3-triazole)]propionates have been prepared and tested as inhibitors of arachidonic acid-induced malondialdehyde formation in human platelets. The obtained products confirmed previous structure-activity relationships. Some of them showed moderate inhibitory activity.
摘要
已经制备了多种新型α-[4-取代-(1,2,3-三唑)]丙酸酯，并作为花生四烯酸诱导的人血小板中丙二醛形成的抑制剂进行了测试。所得产物证实了先前的构效关系。其中一些表现出中等抑制活性。
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