• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年患者术中计算机断层扫描(CT)引导下骨水泥增强椎弓根螺钉置入术后的早期并发症和骨水泥渗漏:八年单中心经验。

Early Complications and Cement Leakage in Elderly Patients Who Have Undergone Intraoperative Computed Tomography (CT)-Guided Cement Augmented Pedicle Screw Placement: Eight-Year Single-Center Experience.

机构信息

Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.

Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.

出版信息

World Neurosurg. 2019 Aug;128:e975-e981. doi: 10.1016/j.wneu.2019.05.047. Epub 2019 May 14.

DOI:10.1016/j.wneu.2019.05.047
PMID:31100522
Abstract

OBJECTIVE

To assess early complications, mortality rate, and cement leakage in elderly patients who had undergone navigation-based pedicle screw placement of the thoracic and lumbar spine.

METHODS

Eighty-six patients older than 65 years of age who had received cement-augmented pedicle screws for various conditions were retrospectively included between May 2008 and December 2016. Complications, mortality, and cement leakage were determined. All patients had a radiograph as a control. In patients with cement leakage seen on radiographs, a computed tomography scan of the surgical area was also obtained.

RESULTS

Average age was 73.4 years (range 65-86 years). A total of 319 vertebral bodies with 637 screws were inserted, of which 458 screws were cement-augmented; 348 (76%) of the augmented screws were placed in the lumbar spine and 110 (24%) in the thoracic spine. Cement leakage occurred in 55 of 86 patients, of whom 52 (60%) were asymptomatic. In all cases with cement leakage (asymptomatic or symptomatic), cement could be found in the perivertebral veins: in the inferior vena cava in 25%, in the epidural space in 7%, in the azygos vein in 5%, and in pulmonary arteries in 7%.

CONCLUSIONS

Our study confirms that the use of cement correlates with a high risk of cement leakage in elderly patients. Using computed tomography navigation for screw placement did not reduce the risk of venous cement leakage, but leakage into the epidural space or through a cortical defect seems to be low.

摘要

目的

评估行导航辅助胸椎和腰椎经皮椎弓根螺钉置钉术的老年患者的早期并发症、死亡率和骨水泥渗漏情况。

方法

回顾性纳入 2008 年 5 月至 2016 年 12 月期间因各种原因接受骨水泥增强椎弓根螺钉治疗的 86 例 65 岁以上老年患者。确定并发症、死亡率和骨水泥渗漏情况。所有患者均行影像学检查作为对照。对影像学检查发现骨水泥渗漏的患者,还进行了手术区域的计算机断层扫描检查。

结果

平均年龄为 73.4 岁(65-86 岁)。共置入 319 个椎体和 637 枚螺钉,其中 458 枚螺钉为骨水泥增强型;348 枚(76%)增强型螺钉置入腰椎,110 枚(24%)置入胸椎。86 例患者中有 55 例发生骨水泥渗漏,其中 52 例(60%)无症状。所有发生骨水泥渗漏(有症状或无症状)的患者,骨水泥均可见于椎旁静脉:下腔静脉 25%,硬膜外间隙 7%,奇静脉 5%,肺动脉 7%。

结论

本研究证实,老年患者使用骨水泥与骨水泥渗漏风险增加相关。使用计算机断层扫描导航进行螺钉放置并不能降低静脉骨水泥渗漏的风险,但似乎很少出现硬膜外间隙或皮质缺损渗漏。

相似文献

1
Early Complications and Cement Leakage in Elderly Patients Who Have Undergone Intraoperative Computed Tomography (CT)-Guided Cement Augmented Pedicle Screw Placement: Eight-Year Single-Center Experience.老年患者术中计算机断层扫描(CT)引导下骨水泥增强椎弓根螺钉置入术后的早期并发症和骨水泥渗漏:八年单中心经验。
World Neurosurg. 2019 Aug;128:e975-e981. doi: 10.1016/j.wneu.2019.05.047. Epub 2019 May 14.
2
Risk of cement leakage and pulmonary embolism by bone cement-augmented pedicle screw fixation of the thoracolumbar spine.骨水泥增强型胸腰椎椎弓根螺钉固定术致骨水泥渗漏及肺栓塞的风险
Spine J. 2017 Jun;17(6):837-844. doi: 10.1016/j.spinee.2017.01.009. Epub 2017 Jan 17.
3
Cement leakage in pedicle screw augmentation: a prospective analysis of 98 patients and 474 augmented pedicle screws.椎弓根螺钉强化术中的骨水泥渗漏:98例患者及474枚强化椎弓根螺钉的前瞻性分析
J Neurosurg Spine. 2016 Jul;25(1):103-9. doi: 10.3171/2015.10.SPINE15511. Epub 2016 Mar 4.
4
The cement leakage in cement-augmented pedicle screw instrumentation in degenerative lumbosacral diseases: a retrospective analysis of 202 cases and 950 augmented pedicle screws.骨水泥强化椎弓根螺钉内固定治疗退变性腰骶疾病中骨水泥渗漏:202 例 950 枚强化椎弓根螺钉的回顾性分析。
Eur Spine J. 2019 Jul;28(7):1661-1669. doi: 10.1007/s00586-019-05985-4. Epub 2019 Apr 27.
5
Risk-benefit analysis of navigation techniques for vertebral transpedicular instrumentation: a prospective study.椎体椎弓根内固定导航技术的风险效益分析:一项前瞻性研究。
Spine J. 2017 Jan;17(1):70-75. doi: 10.1016/j.spinee.2016.08.004. Epub 2016 Aug 5.
6
Economic evaluation comparing intraoperative cone beam CT-based navigation and conventional fluoroscopy for the placement of spinal pedicle screws: a patient-level data cost-effectiveness analysis.基于术中锥形束CT导航与传统透视引导进行脊柱椎弓根螺钉置入的经济学评价:患者层面数据的成本效益分析
Spine J. 2016 Jan 1;16(1):23-31. doi: 10.1016/j.spinee.2015.09.062. Epub 2015 Oct 9.
7
The Influence of Different Injection Hole Designs of Augmented Pedicle Screws on Bone Cement Leakage and Distribution Patterns in Osteoporotic Patients.增强型椎弓根螺钉不同注射孔设计对骨质疏松患者骨水泥渗漏及分布模式的影响。
World Neurosurg. 2022 Jan;157:e40-e48. doi: 10.1016/j.wneu.2021.09.086. Epub 2021 Sep 25.
8
Image-guided spine surgery: a cadaver study comparing conventional open laminoforaminotomy and two image-guided techniques for pedicle screw placement in posterolateral fusion and nonfusion models.影像引导下的脊柱手术:一项尸体研究,比较传统开放性椎板间孔切开术与两种影像引导技术在腰椎后路融合及非融合模型中椎弓根螺钉置入的效果
Spine (Phila Pa 1976). 2002 Nov 15;27(22):2503-8. doi: 10.1097/01.BRS.0000031274.34509.1E.
9
Clinical evaluation of the polymethylmethacrylate-augmented thoracic and lumbar pedicle screw fixation guided by the three-dimensional navigation for the osteoporosis patients.三维导航引导下聚甲基丙烯酸甲酯增强型胸腰椎椎弓根螺钉固定治疗骨质疏松症患者的临床评估
Eur Spine J. 2015 May;24(5):1043-50. doi: 10.1007/s00586-013-3131-8. Epub 2013 Dec 28.
10
High Rate of Pulmonary Cement Embolism after Cement-Augmented Pedicle Screw Fixation: A 12-Year Single-Center Study.经骨水泥增强椎弓根螺钉固定术后肺水泥栓塞的高发生率:一项 12 年单中心研究。
J Neurol Surg A Cent Eur Neurosurg. 2024 Mar;85(2):117-125. doi: 10.1055/s-0043-1761943. Epub 2023 Feb 24.

引用本文的文献

1
A Trajectory Close to the Anterolateral Vertebral Wall Becomes a Risk Factor for Intravascular Cement Leakage During Insertion of Cement-Augmented Fenestrated Pedicle Screws.在置入骨水泥增强型开窗椎弓根螺钉过程中,靠近椎体前外侧壁的轨迹成为血管内骨水泥渗漏的一个危险因素。
Cureus. 2025 Jul 28;17(7):e88942. doi: 10.7759/cureus.88942. eCollection 2025 Jul.
2
Risk Factors for Cement Leakage in Cement-Augmented Pedicle Screw Fixation: A Multicenter Study of 140 Patients and 650 Screws.骨水泥增强椎弓根螺钉固定术中骨水泥渗漏的危险因素:一项针对140例患者和650枚螺钉的多中心研究
Global Spine J. 2025 Jun 29:21925682251357826. doi: 10.1177/21925682251357826.
3
Risk factor analysis of bone cement leakage for polymethylmethacrylate-augmented cannulated pedicle screw fixation in spinal disorders.
聚甲基丙烯酸甲酯增强型空心椎弓根螺钉固定治疗脊柱疾病中骨水泥渗漏的危险因素分析
Heliyon. 2023 Apr 3;9(4):e15167. doi: 10.1016/j.heliyon.2023.e15167. eCollection 2023 Apr.
4
Cardiopulmonary Cement Embolism Following Cement-Augmented Pedicle Screw Fixation: A Narrative Review.经皮椎弓根螺钉固定骨水泥强化后心肺水泥栓塞:叙事性综述。
Medicina (Kaunas). 2023 Feb 19;59(2):407. doi: 10.3390/medicina59020407.
5
Augmentation in fragility fractures, bone of contention: a systematic review.脆性骨折的增加,争议之所在:系统综述。
BMC Musculoskelet Disord. 2022 Dec 2;23(1):1046. doi: 10.1186/s12891-022-06022-0.
6
Case report: Cement entrapped in the inferior vena cava filter after pedicle screw augmentation.病例报告:椎弓根螺钉强化术后骨水泥被困于下腔静脉滤器内。
Front Cardiovasc Med. 2022 Sep 29;9:892025. doi: 10.3389/fcvm.2022.892025. eCollection 2022.