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基层医疗实践中的数字行为体重增加预防干预:成本与成本效益分析

A Digital Behavioral Weight Gain Prevention Intervention in Primary Care Practice: Cost and Cost-Effectiveness Analysis.

作者信息

Krishnan Anirudh, Finkelstein Eric Andrew, Levine Erica, Foley Perry, Askew Sandy, Steinberg Dori, Bennett Gary G

机构信息

Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

Duke Global Digital Health Science Center, Duke University, Durham, NC, United States.

出版信息

J Med Internet Res. 2019 May 17;21(5):e12201. doi: 10.2196/12201.

Abstract

BACKGROUND

Obesity is one of the largest drivers of health care spending but nearly half of the population with obesity demonstrate suboptimal readiness for weight loss treatment. Black women are disproportionately likely to have both obesity and limited weight loss readiness. However, they have been shown to be receptive to strategies that prevent weight gain.

OBJECTIVE

The aim of this study was to evaluate the costs and cost-effectiveness of a digital weight gain prevention intervention (Shape) for black women. Shape consisted of adaptive telephone-based coaching by health system personnel, a tailored skills training curriculum, and patient self-monitoring delivered via a fully automated interactive voice response system.

METHODS

A cost and cost-effectiveness analysis based on a randomized clinical trial of the Shape intervention was conducted from the payer perspective. Costs included those of delivering the program to 91 intervention participants in the trial and were summarized by program elements: self-monitoring, skills training, coaching, and administration. Effectiveness was measured in quality-adjusted life years (QALYs). The primary outcome was the incremental cost per QALY of Shape relative to usual care.

RESULTS

Shape cost an average of US $758 per participant. The base-case model in which quality of life benefits decay linearly to zero 5 years post intervention cessation, generated an incremental cost-effectiveness ratio (ICER) of US $55,264 per QALY. Probabilistic sensitivity analyses suggest an ICER below US $50,000 per QALY and US $100,000 per QALY in 39% and 98% of simulations, respectively. Results are highly sensitive to durability of benefits, rising to US $165,730 if benefits end 6 months post intervention.

CONCLUSIONS

Results suggest that the Shape intervention is cost-effective based on established benchmarks, indicating that it can be a part of a successful strategy to address the nation's growing obesity epidemic in low-income at-risk communities.

摘要

背景

肥胖是医疗保健支出的最大驱动因素之一,但近一半的肥胖人群对减肥治疗的准备情况欠佳。黑人女性肥胖且减肥意愿有限的比例过高。然而,研究表明她们对预防体重增加的策略很容易接受。

目的

本研究旨在评估针对黑人女性的数字体重增加预防干预措施(Shape)的成本和成本效益。Shape包括由卫生系统人员进行的基于电话的适应性指导、量身定制的技能培训课程以及通过全自动交互式语音应答系统进行的患者自我监测。

方法

从付款人的角度,基于Shape干预的随机临床试验进行成本和成本效益分析。成本包括向试验中的91名干预参与者提供该项目的成本,并按项目要素进行汇总:自我监测、技能培训、指导和管理。有效性以质量调整生命年(QALYs)衡量。主要结果是Shape相对于常规护理每QALY的增量成本。

结果

Shape每位参与者的平均成本为758美元。在干预停止后5年生活质量效益线性衰减至零的基础案例模型中,每QALY的增量成本效益比(ICER)为55,264美元。概率敏感性分析表明,在39%和98%的模拟中,每QALY的ICER分别低于50,000美元和100,000美元。结果对效益的持续性高度敏感,如果效益在干预后6个月结束,ICER将升至165,730美元。

结论

结果表明,根据既定基准,Shape干预具有成本效益,这表明它可以成为解决低收入风险社区中全国日益严重的肥胖流行问题的成功策略的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2609/6543798/33863946c83c/jmir_v21i5e12201_fig1.jpg

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